HERPUD1

HERPUD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WGD
Dynodwyr
Cyfenwau	HERPUD1, HERP, Mif1, SUP, homocysteine inducible ER protein with ubiquitin like domain 1
Dynodwyr allanol	OMIM: 608070 HomoloGene: 40973 GeneCards: HERPUD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transmembrane transporter binding • GO:0001948, GO:0016582 protein binding • molecular function • ubiquitin ligase-substrate adaptor activity Cydrannau o'r gell • integral component of membrane • Lewy body core • calcium channel complex • endoplasmic reticulum membrane • bilen • Reticwlwm endoplasmig Prosesau biolegol • negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • ubiquitin-dependent protein catabolic process • negative regulation of intrinsic apoptotic signaling pathway • regulation of protein ubiquitination • regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway • cellular calcium ion homeostasis • endoplasmic reticulum calcium ion homeostasis • response to endoplasmic reticulum stress • PERK-mediated unfolded protein response • positive regulation of ER-associated ubiquitin-dependent protein catabolic process • regulation of ER-associated ubiquitin-dependent protein catabolic process • response to unfolded protein • retrograde protein transport, ER to cytosol • positive regulation of protein binding • endoplasmic reticulum unfolded protein response • protein ubiquitination Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9709	n/a
Ensembl	ENSG00000051108	n/a
UniProt	Q15011	n/a
RefSeq (mRNA)	NM_001010989 NM_001010990 NM_001272103 NM_014685	n/a
RefSeq (protein)	NP_001010989 NP_001259032 NP_055500 NP_001259032.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HERPUD1 yw HERPUD1 a elwir hefyd yn Homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein a Homocysteine inducible ER protein with ubiquitin like domain 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16q13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HERPUD1.

• SUP
• HERP
• Mif1

Llyfryddiaeth

• "The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neurotoxin model of Parkinson disease. ". J Biol Chem. 2009. PMID 19447887.
• "Herp mRNA expression in patients classified according to Lesch's typology. ". Alcohol. 2009. PMID 19251110.
• "Evidence of a novel gene HERPUD1 in polypoidal choroidal vasculopathy. ". Int J Clin Exp Pathol. 2015. PMID 26823705.
• "Herp depletion protects from protein aggregation by up-regulating autophagy. ". Biochim Biophys Acta. 2013. PMID 24120520.
• "The endoplasmic reticulum stress-inducible protein, Herp, is a potential triggering antigen for anti-DNA response.". J Immunol. 2010. PMID 20147634.