HDGFL3

HDGFL3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1N27
Dynodwyr
Cyfenwau	HDGFL3, CGI-142, HDGF-2, HDGF2, HRP-3, HDGFRP3, hepatoma-derived growth factor, related protein 3, HDGF like 3
Dynodwyr allanol	OMIM: 616643 HomoloGene: 32196 GeneCards: HDGFL3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • microtubule binding • tubulin binding • growth factor activity Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell • nucleoplasm • extracellular region Prosesau biolegol • negative regulation of microtubule depolymerization • microtubule polymerization • cell population proliferation • neuron projection development • regulation of signaling receptor activity • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	50810	n/a
Ensembl	ENSG00000166503	n/a
UniProt	Q9Y3E1	n/a
RefSeq (mRNA)	NM_016073	n/a
RefSeq (protein)	NP_057157	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HDGFL3 yw HDGFL3 a elwir hefyd yn HDGF like 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q25.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HDGFL3.

• HDGF2
• HRP-3
• HDGF-2
• CGI-142
• HDGFRP3

Llyfryddiaeth

• "A new member of a hepatoma-derived growth factor gene family can translocate to the nucleus. ". Biochem Biophys Res Commun. 1999. PMID 10581169.
• "Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. ". J Biol Chem. 2004. PMID 15371438.
• "HRP-3 protects the hepatoma cells from glucose deprivation-induced apoptosis. ". Int J Clin Exp Pathol. 2015. PMID 26823754.
• "Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation. ". Biochem Biophys Res Commun. 2013. PMID 24012673.
• "Hepatoma-derived growth factor-related protein-3 interacts with microtubules and promotes neurite outgrowth in mouse cortical neurons.". J Biol Chem. 2009. PMID 19237540.