H2AFZ

H2AZ1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1F66, 3WA9, 4CAY, 4NFT, 5FUG, 5CHL
Dynodwyr
Cyfenwau	H2AZ1, H2A.Z-1, H2A.z, H2A/z, H2AZ, H2A histone family member Z, H2A.Z variant histone 1, H2AFZ
Dynodwyr allanol	OMIM: 142763 HomoloGene: 80218 GeneCards: H2AZ1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleosomal DNA binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA binding • chromatin DNA binding • GO:0001948, GO:0016582 protein binding • RNA polymerase II core promoter sequence-specific DNA binding • protein heterodimerization activity Cydrannau o'r gell • nucleosome • extracellular exosome • Barr body • cnewyllyn cell • Cromosom Prosesau biolegol • cellular response to estradiol stimulus • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3015	n/a
Ensembl	ENSG00000164032	n/a
UniProt	P0C0S5	n/a
RefSeq (mRNA)	NM_002106	n/a
RefSeq (protein)	NP_002097	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn H2AFZ yw H2AFZ a elwir hefyd yn H2A histone family member Z (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn H2AFZ.

• H2AZ
• H2A.z
• H2A/z
• H2A.Z-1

Llyfryddiaeth

• "Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. ". Open Biol. 2016. PMID 27358293.
• "Oncogenic potential of histone-variant H2A.Z.1 and its regulatory role in cell cycle and epithelial-mesenchymal transition in liver cancer. ". Oncotarget. 2016. PMID 26863632.
• "Genetic complementation analysis showed distinct contributions of the N-terminal tail of H2A.Z to epigenetic regulations. ". Genes Cells. 2016. PMID 26833946.
• "Association of common variants in H2AFZ gene with schizophrenia and cognitive function in patients with schizophrenia. ". J Hum Genet. 2015. PMID 26246156.
• "Removal of H2A.Z by INO80 promotes homologous recombination.". EMBO Rep. 2015. PMID 26142279.