GTF2H5

GTF2H5
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1YDL, 2JNJ, 5IY8, 5IY6, 5IY7, 5IVW, 5IY9
Dynodwyr
Cyfenwau	GTF2H5, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA, bA120J8.2, TTD3, general transcription factor IIH subunit 5
Dynodwyr allanol	OMIM: 608780 HomoloGene: 45635 GeneCards: GTF2H5
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• rDNA binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• nucleoplasm; • nucleolus; • GO:0000441 transcription factor TFIIH core complex; • cnewyllyn cell; • transcription factor TFIID complex; • transcription factor TFIIH holo complex;
Prosesau biolegol	• termination of RNA polymerase I transcription; • GO:0009373 regulation of transcription, DNA-templated; • transcription initiation from RNA polymerase I promoter; • transcription elongation from RNA polymerase II promoter; • 7-methylguanosine mRNA capping; • transcription by RNA polymerase II; • transcription, DNA-templated; • cellular response to DNA damage stimulus; • global genome nucleotide-excision repair; • cellular response to gamma radiation; • rRNA processing; • transcription-coupled nucleotide-excision repair; • transcription initiation from RNA polymerase II promoter; • nucleotide-excision repair, DNA incision; • nucleotide-excision repair, preincision complex assembly; • nucleotide-excision repair; • nucleotide-excision repair, DNA incision, 5'-to lesion; • GO:0100026 DNA repair; • nucleotide-excision repair, preincision complex stabilization; • GO:0001183 transcription elongation from RNA polymerase I promoter; • phosphorylation of RNA polymerase II C-terminal domain; • nucleotide-excision repair, DNA duplex unwinding; • nucleotide-excision repair, DNA incision, 3'-to lesion;
	Sources:Amigo / QuickGO
Orthologau
	404672
	n/a
	ENSG00000272047
	n/a
	Q6ZYL4
	n/a
	NM_207118
	n/a
	NP_997001
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GTF2H5 yw GTF2H5 a elwir hefyd yn General transcription factor IIH subunit 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q25.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GTF2H5.

TTD
TFB5
TTD3
TTDA
TFIIH
TTD-A
TGF2H5
C6orf175
bA120J8.2

Llyfryddiaeth

"p8/TTD-A as a repair-specific TFIIH subunit. ". Mol Cell. 2006. PMID 16427011.
"Molecular evolution of the second ancient human mariner transposon, Hsmar2, illustrates patterns of neutral evolution in the human genome lineage. ". Gene. 1997. PMID 9461396.
"The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients. ". J Gynecol Oncol. 2016. PMID 26463438.
"In vivo interactions of TTDA mutant proteins within TFIIH. ". J Cell Sci. 2013. PMID 23729738.
"Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy.". J Mol Biol. 2007. PMID 17350038.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] GTF2H5 - Cronfa NCBI

[1]

[2]