GTF2H1

GTF2H1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1PFJ, 2DII, 2RNR, 2RUK, 2RVB
Dynodwyr
Cyfenwau	GTF2H1, BTF2, P62, TFB1, TFIIH, general transcription factor IIH subunit 1
Dynodwyr allanol	OMIM: 189972 HomoloGene: 3885 GeneCards: GTF2H1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein kinase activity • ATP-dependent activity, acting on DNA • chromatin binding • GO:0001948, GO:0016582 protein binding • RNA polymerase II CTD heptapeptide repeat kinase activity Cydrannau o'r gell • nucleoplasm • transcription factor TFIIH holo complex • cnewyllyn cell • GO:0000441 transcription factor TFIIH core complex Prosesau biolegol • termination of RNA polymerase I transcription • regulation of cyclin-dependent protein serine/threonine kinase activity • GO:0009373 regulation of transcription, DNA-templated • transcription initiation from RNA polymerase I promoter • transcription elongation from RNA polymerase II promoter • 7-methylguanosine mRNA capping • transcription by RNA polymerase II • transcription, DNA-templated • cellular response to DNA damage stimulus • global genome nucleotide-excision repair • transcription-coupled nucleotide-excision repair • transcription initiation from RNA polymerase II promoter • nucleotide-excision repair, DNA incision • GO:0100026 DNA repair • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • nucleotide-excision repair, preincision complex stabilization • nucleotide-excision repair • nucleotide-excision repair, DNA incision, 5'-to lesion • nucleotide-excision repair, preincision complex assembly • transcription by RNA polymerase I • phosphorylation of RNA polymerase II C-terminal domain • nucleotide-excision repair, DNA duplex unwinding • nucleotide-excision repair, DNA incision, 3'-to lesion • GO:0001183 transcription elongation from RNA polymerase I promoter Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2965	n/a
Ensembl	ENSG00000110768 ENSG00000288114	n/a
UniProt	P32780	n/a
RefSeq (mRNA)	NM_001142307 NM_005316	n/a
RefSeq (protein)	NP_001135779 NP_005307	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GTF2H1 yw GTF2H1 a elwir hefyd yn General transcription factor IIH subunit 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11p15.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GTF2H1.

• P62
• BTF2
• TFB1
• TFIIH

Llyfryddiaeth

• "Genetic variants in GTF2H1 and risk of lung cancer: a case-control analysis in a Chinese population. ". Lung Cancer. 2009. PMID 18692935.
• "Rapid switching of TFIIH between RNA polymerase I and II transcription and DNA repair in vivo. ". Mol Cell. 2002. PMID 12453423.
• "Ku70/Ku80 protein complex inhibits the binding of nucleotide excision repair proteins on linear DNA in vitro. ". J Mol Biol. 1998. PMID 9837719.
• "A high-resolution integrated physical, cytogenetic, and genetic map of human chromosome 11: distal p13 to proximal p15.1. ". Genomics. 1995. PMID 7789978.
• "Cloning of the 62-kilodalton component of basic transcription factor BTF2.". Science. 1992. PMID 1529339.