GTF2B

GTF2B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1C9B, 1DL6, 1RLY, 1RO4, 1TFB, 1VOL, 2PHG, 5IY7, 5IYA, 5IY6, 5IY9, 5IYB, 5IYD, 5IY8, 5IYC
Dynodwyr
Cyfenwau	GTF2B, TF2B, TFIIB, general transcription factor IIB
Dynodwyr allanol	OMIM: 189963 HomoloGene: 1158 GeneCards: GTF2B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • transcription factor binding • GO:0001948, GO:0016582 protein binding • metal ion binding • thyroid hormone receptor binding • TBP-class protein binding • RNA polymerase II complex binding • acetyltransferase activity • promoter-specific chromatin binding • RNA polymerase II core promoter sequence-specific DNA binding • zinc ion binding • histone acetyltransferase activity • transferase activity • acyltransferase activity • RNA polymerase II complex recruiting activity • GO:0000983 RNA polymerase II general transcription initiation factor activity Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • transcription factor TFIID complex • nuclear body • transcription preinitiation complex • Cromosom • protein-DNA complex • RNA polymerase II transcription regulator complex Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of viral transcription • snRNA transcription by RNA polymerase II • GO:0022415 viral process • transcription preinitiation complex assembly • positive regulation of core promoter binding • transcription initiation from RNA polymerase II promoter • protein acetylation • positive regulation by host of viral transcription • positive regulation of transcription initiation from RNA polymerase II promoter • transcriptional start site selection at RNA polymerase II promoter • transcription by RNA polymerase II • RNA polymerase II preinitiation complex assembly • RNA polymerase II core complex assembly • histone acetylation • DNA-templated transcription, initiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2959	n/a
Ensembl	ENSG00000137947	n/a
UniProt	Q00403	n/a
RefSeq (mRNA)	NM_001514	n/a
RefSeq (protein)	NP_001505	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GTF2B yw GTF2B a elwir hefyd yn General transcription factor IIB (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GTF2B.

• TF2B
• TFIIB

Llyfryddiaeth

• "In vitro fluorescence studies of transcription factor IIB-DNA interaction. ". Acta Biochim Pol. 2015. PMID 26284261.
• "Evaluation of the Intrinsic Zn(II) Affinity of a Cys3His1 Site in the Absence of Protein Folding Effects. ". Inorg Chem. 2015. PMID 26016528.
• "A new paradigm for transcription factor TFIIB functionality. ". Sci Rep. 2014. PMID 24441171.
• "General transcription factor IIb overexpression and a potential link to proliferation in human hepatocellular carcinoma. ". Pathol Oncol Res. 2013. PMID 23055019.
• "The TFIIB tip domain couples transcription initiation to events involved in RNA processing.". J Biol Chem. 2010. PMID 20880846.