GSTZ1

GSTZ1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FW1
Dynodwyr
Cyfenwau	GSTZ1, GSTZ1-1, MAAI, MAI, glutathione S-transferase zeta 1, MAAID
Dynodwyr allanol	OMIM: 603758 HomoloGene: 7747 GeneCards: GSTZ1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • glutathione peroxidase activity • glutathione transferase activity • maleylacetoacetate isomerase activity • isomerase activity • catalytic activity • protein homodimerization activity • GO:0001948, GO:0016582 protein binding • identical protein binding • hydrolase activity, acting on acid halide bonds, in C-halide compounds Cydrannau o'r gell • cytoplasm • cytosol • mitocondria • mitochondrial matrix Prosesau biolegol • aromatic amino acid family metabolic process • metabolaeth • L-phenylalanine catabolic process • glutathione metabolic process • glutathione derivative biosynthetic process • tyrosine catabolic process • cellular oxidant detoxification • regulation of acetyl-CoA biosynthetic process from pyruvate Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2954	n/a
Ensembl	ENSG00000100577	n/a
UniProt	O43708	n/a
RefSeq (mRNA)	NM_001312660 NM_001513 NM_145870 NM_145871 NM_001363703	n/a
RefSeq (protein)	NP_001299589 NP_665877 NP_665878 NP_001350632	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GSTZ1 yw GSTZ1 a elwir hefyd yn Glutathione S-transferase zeta 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q24.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GSTZ1.

• MAI
• MAAI
• MAAID
• GSTZ1-1

Llyfryddiaeth

• "Hypersuccinylacetonaemia and normal liver function in maleylacetoacetate isomerase deficiency. ". J Med Genet. 2017. PMID 27876694.
• "The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression. ". Pharmacogenet Genomics. 2015. PMID 25738370.
• "Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children. ". J Clin Pharmacol. 2015. PMID 25079374.
• "Glutathione S-transferase Z1 (GSTZ1) gene polymorphism in gastric cancer: a preliminary study in a Turkish population. ". Lab Med. 2014. PMID 24719983.
• "Characterization of catalytic activity and structure of selenocysteine-containing hGSTZ1c-1c based on site-directed mutagenesis and computational analysis.". IUBMB Life. 2013. PMID 23299908.