GSTA1

GSTA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1GSD, 1GSE, 1GSF, 1GUH, 1K3L, 1K3O, 1K3Y, 1PKW, 1PKZ, 1PL1, 1PL2, 1USB, 1XWG, 1YDK, 2R3X, 2R6K, 3I69, 3I6A, 3IK9, 3KTL, 3L0H, 3Q74, 3U6V, 3ZFB, 3ZFL, 4HJ2
Dynodwyr
Cyfenwau	GSTA1, GST2, GSTA1-1, GTH1, GST-epsilon, glutathione S-transferase alpha 1
Dynodwyr allanol	OMIM: 138359 HomoloGene: 130684 GeneCards: GSTA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • glutathione peroxidase activity • glutathione transferase activity • steroid delta-isomerase activity • peroxidase activity • oxidoreductase activity • isomerase activity Cydrannau o'r gell • cytoplasm • extracellular exosome • cytosol Prosesau biolegol • metabolaeth • epithelial cell differentiation • glutathione derivative biosynthetic process • glutathione metabolic process • cellular oxidant detoxification • linoleic acid metabolic process • prostaglandin metabolic process • xenobiotic metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2938	n/a
Ensembl	ENSG00000243955	n/a
UniProt	P08263	n/a
RefSeq (mRNA)	NM_145740 NM_001319059	n/a
RefSeq (protein)	NP_001305988 NP_665683	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GSTA1 yw GSTA1 a elwir hefyd yn Glutathione S-transferase alpha 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p12.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GSTA1.

• GST2
• GTH1
• GSTA1-1
• GST-epsilon

Llyfryddiaeth

• "Dual Lifetimes for Complexes between Glutathione-S-transferase (hGSTA1-1) and Product-like Ligands Detected by Single-Molecule Fluorescence Imaging. ". Biochemistry. 2017. PMID 28677395.
• "The rs3957357C>T SNP in GSTA1 Is Associated with a Higher Risk of Occurrence of Hepatocellular Carcinoma in European Individuals. ". PLoS One. 2016. PMID 27936036.
• "Enzymatic Activity of Glutathione S-Transferase and Dental Fluorosis Among Children Receiving Two Different Levels of Naturally Fluoridated Water. ". Biol Trace Elem Res. 2017. PMID 27449362.
• "Population pharmacokinetics and pharmacodynamics of busulfan with GSTA1 polymorphisms in patients undergoing allogeneic hematopoietic stem cell transplantation. ". Pharmacogenomics. 2015. PMID 26419450.
• "GSTA1 gene variation associated with gestational hypertension and its involvement in pregnancy-related pathogenic conditions.". Eur J Obstet Gynecol Reprod Biol. 2015. PMID 26321410.