GRM7

GRM7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3MQ4, 5C5C
Dynodwyr
Cyfenwau	GRM7, GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87, glutamate metabotropic receptor 7, NEDSHBA
Dynodwyr allanol	OMIM: 604101 HomoloGene: 20233 GeneCards: GRM7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • glutamate receptor activity • calcium ion binding • PDZ domain binding • serine binding • G protein-coupled receptor activity • group III metabotropic glutamate receptor activity • adenylate cyclase inhibitor activity • signal transducer activity • glutamate binding • calcium channel regulator activity Cydrannau o'r gell • integral component of membrane • postsynaptic membrane • bilen • receptor complex • Cellbilen • integral component of plasma membrane • dendritic shaft • presynaptic active zone • axon • dendrite • cell cortex • asymmetric synapse • presynaptic membrane Prosesau biolegol • negative regulation of glutamate secretion • response to stimulus • clyw • behavioral fear response • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway • GO:0072468 signal transduction • regulation of cyclase activity • regulation of synaptic transmission, glutamatergic • chemical synaptic transmission • G protein-coupled receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2917	n/a
Ensembl	ENSG00000196277	n/a
UniProt	Q14831	n/a
RefSeq (mRNA)	NM_000844 NM_181874 NM_181875	n/a
RefSeq (protein)	NP_000835 NP_870989	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GRM7 yw GRM7 a elwir hefyd yn Glutamate metabotropic receptor 7 a Metabotropic glutamate receptor 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p26.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GRM7.

• GLUR7
• MGLU7
• GPRC1G
• MGLUR7
• PPP1R87

Llyfryddiaeth

• "The GRM7 gene, early response to risperidone, and schizophrenia: a genome-wide association study and a confirmatory pharmacogenetic analysis. ". Pharmacogenomics J. 2017. PMID 26856250.
• "Association study of GRM7 polymorphisms and schizophrenia in the Chinese Han population. ". Neurosci Lett. 2015. PMID 26254163.
• "Lack of association between the GRM7 gene and attention deficit hyperactivity disorder. ". Psychiatr Genet. 2014. PMID 25360607.
• "Allelic association, DNA resequencing and copy number variation at the metabotropic glutamate receptor GRM7 gene locus in bipolar disorder. ". Am J Med Genet B Neuropsychiatr Genet. 2014. PMID 24804643.
• "Association of GRM7 variants with different phenotype patterns of age-related hearing impairment in an elderly male Han Chinese population.". PLoS One. 2013. PMID 24146964.