GRM3

GRM3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3SM9, 4XAR, 5CNK, 5CNM
Dynodwyr
Cyfenwau	GRM3, GLUR3, GPRC1C, MGLUR3, mGlu3, glutamate metabotropic receptor 3
Dynodwyr allanol	OMIM: 601115 HomoloGene: 651 GeneCards: GRM3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • glutamate receptor activity • group II metabotropic glutamate receptor activity • calcium channel regulator activity • signal transducer activity • G protein-coupled receptor activity Cydrannau o'r gell • integral component of membrane • axon • neuron projection • dendritic spine • postsynaptic membrane • integral component of plasma membrane • GO:0097483, GO:0097481 postsynaptic density • bilen • Cellbilen • presynaptic membrane • glutamatergic synapse • integral component of postsynaptic membrane • integral component of presynaptic membrane Prosesau biolegol • negative regulation of adenylate cyclase activity • GO:0072468 signal transduction • chemical synaptic transmission • regulation of synaptic transmission, glutamatergic • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2913	n/a
Ensembl	ENSG00000198822	n/a
UniProt	Q14832	n/a
RefSeq (mRNA)	NM_000840 NM_001363522	n/a
RefSeq (protein)	NP_000831 NP_001350451	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GRM3 yw GRM3 a elwir hefyd yn Metabotropic glutamate receptor 3 a Glutamate metabotropic receptor 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q21.11-q21.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GRM3.

• GLUR3
• mGlu3
• GPRC1C
• MGLUR3

Llyfryddiaeth

• "Metabotropic glutamate receptor 3 is involved in B-cell-related tumor apoptosis. ". Int J Oncol. 2016. PMID 27431857.
• "Evaluation of relationship between GRM3 polymorphisms and cognitive function in schizophrenia of Han Chinese. ". Psychiatry Res. 2015. PMID 26187343.
• "Effect of metabotropic glutamate receptor-3 variants on prefrontal brain activity in schizophrenia: An imaging genetics study using multi-channel near-infrared spectroscopy. ". Prog Neuropsychopharmacol Biol Psychiatry. 2015. PMID 25914064.
• "mGluR3 promotes proliferation of human embryonic cortical neural progenitor cells by activating ERK1/2 and JNK2 signaling pathway in vitro. ". Cell Mol Biol (Noisy-le-grand). 2014. PMID 25198581.
• "Pharmacogenetic associations of the type-3 metabotropic glutamate receptor (GRM3) gene with working memory and clinical symptom response to antipsychotics in first-episode schizophrenia.". Psychopharmacology (Berl). 2015. PMID 25096017.