GRIP1

GRIP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JIL
Dynodwyr
Cyfenwau	GRIP1, GRIP, glutamate receptor interacting protein 1, FRASRS3
Dynodwyr allanol	OMIM: 604597 HomoloGene: 12938 GeneCards: GRIP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • beta-catenin binding • GO:0001105 transcription coactivator activity • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • androgen receptor binding • glucocorticoid receptor binding • signaling receptor complex adaptor activity Cydrannau o'r gell • recycling endosome • cytosol • postsynaptic membrane • bilen • Cellbilen • synapse • cell junction • dendrite • Reticwlwm endoplasmig • membrane raft • neuron projection • GO:0016023 cytoplasmic vesicle • glutamatergic synapse Prosesau biolegol • GO:0034613 protein localization • androgen receptor signaling pathway • GO:0007243 intracellular signal transduction • dendrite development • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • neurotransmitter receptor transport, endosome to postsynaptic membrane • vesicle-mediated transport in synapse • positive regulation of neuron projection arborization • positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23426	n/a
Ensembl	ENSG00000155974	n/a
UniProt	Q9Y3R0	n/a
RefSeq (mRNA)	NM_001178074 NM_021150 NM_001366722 NM_001366723 NM_001366724 NM_001379345 NM_001379346 NM_001379347 NM_001379348 NM_001379349 NM_001379351	n/a
RefSeq (protein)	NP_001171545 NP_066973 NP_001353651 NP_001353652 NP_001353653 NP_001366274 NP_001366275 NP_001366276 NP_001366277 NP_001366278 NP_001366280	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GRIP1 yw GRIP1 a elwir hefyd yn Glutamate receptor-interacting protein 1 a Glutamate receptor interacting protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q14.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GRIP1.

• GRIP
• FRASRS3

Llyfryddiaeth

• "Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1. ". J Mol Biol. 2008. PMID 18155042.
• "Metabolism, cytoskeleton and cellular signalling in the grip of protein Nepsilon - and O-acetylation. ". EMBO Rep. 2007. PMID 17545996.
• "Mutations in GRIP1 cause Fraser syndrome. ". J Med Genet. 2012. PMID 22510445.
• "No association of GRIP1 gene polymorphisms with schizophrenia in Chinese population. ". Prog Neuropsychopharmacol Biol Psychiatry. 2007. PMID 17303296.
• "Gephyrin interacts with the glutamate receptor interacting protein 1 isoforms at GABAergic synapses.". J Neurochem. 2008. PMID 18315564.