GRHPR

GRHPR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2GCG, 2H1S, 2Q50, 2WWR
Dynodwyr
Cyfenwau	GRHPR, GLXR, GLYD, PH2, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate and hydroxypyruvate reductase
Dynodwyr allanol	OMIM: 604296 HomoloGene: 49088 GeneCards: GRHPR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • glycerate dehydrogenase activity • GO:0050229 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor • protein homodimerization activity • NAD binding • carboxylic acid binding • NADP binding • NADPH binding • oxidoreductase activity • hydroxypyruvate reductase activity • glyoxylate reductase (NADP+) activity Cydrannau o'r gell • cytoplasm • peroxisomal matrix • extracellular exosome • cytosol Prosesau biolegol • dicarboxylic acid metabolic process • Ysgarthu • protein complex oligomerization • metabolaeth • cellular nitrogen compound metabolic process • glyoxylate metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9380	n/a
Ensembl	ENSG00000137106	n/a
UniProt	Q9UBQ7	n/a
RefSeq (mRNA)	NM_012203	n/a
RefSeq (protein)	NP_036335	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GRHPR yw GRHPR a elwir hefyd yn Glyoxylate and hydroxypyruvate reductase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GRHPR.

• PH2
• GLXR
• GLYD

Llyfryddiaeth

• "Late diagnosis of primary hyperoxaluria type 2 in the adult: effect of a novel mutation in GRHPR gene on enzymatic activity and molecular modeling. ". J Urol. 2009. PMID 19296982.
• "Identification of missense, nonsense, and deletion mutations in the GRHPR gene in patients with primary hyperoxaluria type II (PH2). ". Hum Genet. 2000. PMID 11030416.
• "Ethnic differences in GRHPR mutations in patients with primary hyperoxaluria type 2. ". Clin Genet. 2014. PMID 24116921.
• "Glyoxylate reductase/hydroxypyruvate reductase: a novel prognostic marker for hepatocellular carcinoma patients after curative resection. ". Pathobiology. 2013. PMID 23486161.
• Primary Hyperoxaluria Type 2. 1993. PMID 20301742.