GNAI3

GNAI3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S
Dynodwyr
Cyfenwau	GNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A
Dynodwyr allanol	OMIM: 139370 HomoloGene: 55975 GeneCards: GNAI3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signal transducer activity • metal ion binding • protein domain specific binding • nucleotide binding • GTPase activating protein binding • guanyl nucleotide binding • GDP binding • G protein-coupled receptor binding • G-protein beta/gamma-subunit complex binding • G protein-coupled serotonin receptor binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • GTP binding Cydrannau o'r gell • extracellular exosome • lysosomal membrane • cytoplasm • microtubule organizing center • Golgi apparatus • heterotrimeric G-protein complex • bilen • centrosome • midbody • membrane raft • zymogen granule • Cytosgerbwd • Cellbilen • cnewyllyn cell • nucleolus • Golgi membrane • endoplasmic reticulum membrane Prosesau biolegol • cell cycle • GO:0072468 signal transduction • negative regulation of adenylate cyclase activity • GTP metabolic process • Cellraniad • vesicle fusion • dopamine receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • protein folding • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • GO:0015915 transport • positive regulation of macroautophagy • G protein-coupled receptor signaling pathway • brain development • positive regulation of superoxide anion generation • positive regulation of NAD(P)H oxidase activity • positive regulation of vascular associated smooth muscle cell proliferation • negative regulation of apoptotic signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2773	n/a
Ensembl	ENSG00000065135	n/a
UniProt	P08754	n/a
RefSeq (mRNA)	NM_006496	n/a
RefSeq (protein)	NP_006487	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GNAI3 yw GNAI3 a elwir hefyd yn G protein subunit alpha i3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GNAI3.

• 87U6
• ARCND1

Llyfryddiaeth

• "GNAI3: Another Candidate Gene to Screen in Persons with Ocular Albinism. ". PLoS One. 2016. PMID 27607449.
• "Novel variants in GNAI3 associated with auriculocondylar syndrome strengthen a common dominant negative effect. ". Eur J Hum Genet. 2015. PMID 25026904.
• "Changes in expression of adenyl cyclase activity in human endometrium during hormone replacement therapy and ovarian stimulation. ". Mol Hum Reprod. 1999. PMID 10508224.
• "Leukotriene D4-induced activation and translocation of the G-protein alpha i3-subunit in human epithelial cells. ". Biochem Biophys Res Commun. 1996. PMID 8806649.
• "Differential coupling of m2 and m4 muscarinic receptors to inhibition of adenylyl cyclase by Gi alpha and G(o)alpha subunits.". J Biol Chem. 1995. PMID 7608168.