GNA13

GNA13
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1SHZ, 1ZCB, 3AB3, 3CX6, 3CX7, 3CX8
Dynodwyr
Cyfenwau	GNA13, G13, G protein subunit alpha 13, HG1N
Dynodwyr allanol	OMIM: 604406 HomoloGene: 55976 GeneCards: GNA13
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • G-protein beta/gamma-subunit complex binding • type 1 angiotensin receptor binding • GTP binding • D5 dopamine receptor binding • signal transducer activity • metal ion binding • GO:0001948, GO:0016582 protein binding • guanyl nucleotide binding • G protein-coupled receptor binding • guanyl-nucleotide exchange factor activity • GO:0006184 GTPase activity Cydrannau o'r gell • bilen • focal adhesion • melanosome • brush border membrane • heterotrimeric G-protein complex • extracellular exosome • cnewyllyn cell • cytoplasm • cytosol • Cellbilen Prosesau biolegol • cell differentiation • GO:0007243 intracellular signal transduction • regulation of cell migration • adenylate cyclase-activating G protein-coupled receptor signaling pathway • positive regulation of cytosolic calcium ion concentration • small GTPase mediated signal transduction • in utero embryonic development • platelet activation • activation of phospholipase D activity • Rho protein signal transduction • angiogenesis • regulation of cell shape • branching involved in blood vessel morphogenesis • GO:0072468 signal transduction • positive regulation of apoptotic process • regulation of small GTPase mediated signal transduction • G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10672	n/a
Ensembl	ENSG00000120063	n/a
UniProt	Q14344	n/a
RefSeq (mRNA)	NM_001282425 NM_006572	n/a
RefSeq (protein)	NP_001269354 NP_006563	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GNA13 yw GNA13 a elwir hefyd yn G protein subunit alpha 13 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GNA13.

• G13

Llyfryddiaeth

• "Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs. ". Cell Signal. 2007. PMID 17449226.
• "Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics. ". J Proteomics. 2017. PMID 28214564.
• "GNA13 as a prognostic factor and mediator of gastric cancer progression. ". Oncotarget. 2016. PMID 26735177.
• "Gα13 Switch Region 2 Binds to the Talin Head Domain and Activates αIIbβ3 Integrin in Human Platelets. ". J Biol Chem. 2015. PMID 26292217.
• "Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing.". Blood. 2013. PMID 23699601.