GLUD1

GLUD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1L1F, 1NR1
Dynodwyr
Cyfenwau	GLUD1, GDH, GDH1, GLUD, glutamate dehydrogenase 1, hGDH1
Dynodwyr allanol	OMIM: 138130 HomoloGene: 55885 GeneCards: GLUD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • ADP binding • GTP binding • leucine binding • GO:0001948, GO:0016582 protein binding • NAD+ binding • identical protein binding • oxidoreductase activity • ATP binding • glutamate dehydrogenase [NAD(P)+ activity] • glutamate dehydrogenase (NAD+) activity • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor Cydrannau o'r gell • cytoplasm • mitochondrial matrix • mitocondria Prosesau biolegol • glutamate catabolic process • glutamate biosynthetic process • substantia nigra development • cellular amino acid metabolic process • cellular amino acid biosynthetic process • glutamine metabolic process • tricarboxylic acid metabolic process • positive regulation of insulin secretion • mitochondrion organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2746	n/a
Ensembl	ENSG00000148672	n/a
UniProt	P00367	n/a
RefSeq (mRNA)	NM_005271 NM_001318900 NM_001318901 NM_001318902 NM_001318904 NM_001318905 NM_001318906	n/a
RefSeq (protein)	NP_001305829 NP_001305830 NP_001305831 NP_001305833 NP_001305834 NP_001305835 NP_005262	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GLUD1 yw GLUD1 a elwir hefyd yn Glutamate dehydrogenase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q23.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GLUD1.

• GDH
• GDH1
• GLUD

Llyfryddiaeth

• "Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase. ". Biochemistry. 2016. PMID 27808506.
• "Robust regulation of hepatic pericentral amination by glutamate dehydrogenase kinetics. ". Integr Biol (Camb). 2016. PMID 27747338.
• "Hyperinsulinism-hyperammonemia syndrome: a de novo mutation of the GLUD1 gene in twins and a review of the literature. ". J Pediatr Endocrinol Metab. 2016. PMID 27383869.
• "Early Presentation of Hyperinsulinism/Hyperammonemia Syndrome in Three Serbian Patients. ". J Clin Res Pediatr Endocrinol. 2016. PMID 26759084.
• "Uncovering the molecular pathogenesis of congenital hyperinsulinism by panel gene sequencing in 32 Chinese patients.". Mol Genet Genomic Med. 2015. PMID 26740944.