GLRX

GLRX
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1B4Q, 1JHB, 4RQR
Dynodwyr
Cyfenwau	GLRX, GRX, GRX1, glutaredoxin
Dynodwyr allanol	OMIM: 600443 HomoloGene: 37566 GeneCards: GLRX
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein-disulfide reductase activity • electron transfer activity • glutathione oxidoreductase activity • protein N-terminus binding • glutathione disulfide oxidoreductase activity Cydrannau o'r gell • cytoplasm • cytosol • extracellular exosome • mitocondria • cnewyllyn cell Prosesau biolegol • positive regulation of sodium ion transmembrane transporter activity • nucleobase-containing small molecule interconversion • positive regulation of membrane potential • protein deglutathionylation • cell redox homeostasis • electron transport chain Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2745	n/a
Ensembl	ENSG00000173221	n/a
UniProt	P35754	n/a
RefSeq (mRNA)	NM_002064 NM_001118890 NM_001243658 NM_001243659	n/a
RefSeq (protein)	NP_001112362 NP_001230587 NP_001230588 NP_002055	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GLRX yw GLRX a elwir hefyd yn Glutaredoxin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q15.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GLRX.

• GRX
• GRX1

Llyfryddiaeth

• "Reduction potentials of protein disulfides and catalysis of glutathionylation and deglutathionylation by glutaredoxin enzymes. ". Biochem J. 2017. PMID 28963348.
• "Glutaredoxin 1 (GRX1) inhibits oxidative stress and apoptosis of chondrocytes by regulating CREB/HO-1 in osteoarthritis. ". Mol Immunol. 2017. PMID 28843170.
• "Determination of glutathione redox potential and pH value in subcellular compartments of malaria parasites. ". Free Radic Biol Med. 2017. PMID 28062360.
• "Glutaredoxin Desensitizes Lens to Oxidative Stress by Connecting and Integrating Specific Signaling and Transcriptional Regulation for Antioxidant Response. ". Cell Physiol Biochem. 2016. PMID 27744453.
• "Glutaredoxin 1 (Grx1) Protects Human Retinal Pigment Epithelial Cells From Oxidative Damage by Preventing AKT Glutathionylation.". Invest Ophthalmol Vis Sci. 2015. PMID 25788646.