GGA1

GGA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1J2J, 1JWF, 1JWG, 1NA8, 1NAF, 1NWM, 1O3X, 1OM9, 1OXZ, 1PY1, 1UJJ, 1UJK, 1X79, 2DWX, 2DWY, 3G2S, 3G2T, 3G2U, 3G2V, 3G2W
Dynodwyr
Cyfenwau	GGA1, golgi associated, gamma adaptin ear containing, ARF binding protein 1
Dynodwyr allanol	OMIM: 606004 HomoloGene: 39250 GeneCards: GGA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • molecular function Cydrannau o'r gell • endosome • Golgi apparatus • endosome membrane • intracellular anatomical structure • bilen • intracellular membrane-bounded organelle • clathrin adaptor complex • nucleoplasm • early endosome membrane • early endosome • cytosol • GO:0009327 protein-containing complex Prosesau biolegol • protein transport • intracellular protein transport • toxin transport • GO:1903364 positive regulation of protein catabolic process • vesicle-mediated transport • GO:0015915 transport • Golgi to plasma membrane transport • GO:0034613 protein localization • protein localization to cell surface • retrograde transport, endosome to Golgi • Golgi to plasma membrane protein transport • protein localization to ciliary membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	26088	n/a
Ensembl	ENSG00000100083	n/a
UniProt	Q9UJY5	n/a
RefSeq (mRNA)	NM_001001560 NM_001001561 NM_001172687 NM_001172688 NM_013365 NM_001363771	n/a
RefSeq (protein)	NP_001001560 NP_001166158 NP_001166159 NP_037497 NP_001350700	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GGA1 yw GGA1 a elwir hefyd yn ADP-ribosylation factor-binding protein GGA1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q13.1.

Llyfryddiaeth

• "GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network. ". Mol Cell Neurosci. 2005. PMID 15886016.
• "Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5. ". EMBO J. 2004. PMID 15457209.
• "Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS). ". BMC Bioinformatics. 2010. PMID 20214818.
• "Thirst and hydration: physiology and consequences of dysfunction. ". Physiol Behav. 2010. PMID 20211637.
• "GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide.". J Neurosci. 2006. PMID 17151287.