GFRA1

GFRA1
Dynodwyr
Cyfenwau	GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1, GDNF family receptor alpha 1
Dynodwyr allanol	OMIM: 601496 HomoloGene: 3855 GeneCards: GFRA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signaling receptor binding • glial cell-derived neurotrophic factor receptor activity • signaling receptor activity Cydrannau o'r gell • anchored component of membrane • extracellular exosome • bilen • extrinsic component of membrane • intracellular anatomical structure • Cellbilen • external side of plasma membrane • receptor complex Prosesau biolegol • cell surface receptor signaling pathway • nervous system development • MAPK cascade • glial cell-derived neurotrophic factor receptor signaling pathway • axon guidance • regulation of molecular function Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2674	n/a
Ensembl	ENSG00000151892	n/a
UniProt	P56159	n/a
RefSeq (mRNA)	NM_001145453 NM_005264 NM_145793 NM_001348096 NM_001348098 NM_001348099	n/a
RefSeq (protein)	NP_001138925 NP_005255 NP_665736 NP_001335025 NP_001335027 NP_001335028 NP_001369485 NP_001369486 NP_001369487 NP_001369488 NP_001369489 NP_001369490	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GFRA1 yw GFRA1 a elwir hefyd yn GDNF family receptor alpha 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GFRA1.

• GDNFR
• RET1L
• RETL1
• TRNR1
• GDNFRA
• GFR-ALPHA-1

Llyfryddiaeth

• "Identification of a surface for binding to the GDNF-GFR alpha 1 complex in the first cadherin-like domain of RET. ". J Biol Chem. 2003. PMID 14514671.
• "Glial cell line-derived neurotrophic factor family receptors are abnormally expressed in aganglionic bowel of a subpopulation of patients with Hirschsprung's disease. ". Lab Invest. 2002. PMID 12065680.
• "Deficiency of GDNF Receptor GFRα1 in Alzheimer's Neurons Results in Neuronal Death. ". J Neurosci. 2014. PMID 25253858.
• "Expression of glial cell line-derived neurotropic factor receptor alpha-1 in immature teratomas. ". Am J Clin Pathol. 2008. PMID 19019765.
• "A role for glial cell derived neurotrophic factor induced expression by inflammatory cytokines and RET/GFR alpha 1 receptor up-regulation in breast cancer.". Cancer Res. 2007. PMID 18089803.