GEM

GEM
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CJW, 2G3Y, 2HT6
Dynodwyr
Cyfenwau	GEM, KIR, GTP binding protein overexpressed in skeletal muscle
Dynodwyr allanol	OMIM: 600164 HomoloGene: 38024 GeneCards: GEM
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • GO:0001948, GO:0016582 protein binding • magnesium ion binding • calmodulin binding • GDP binding • GO:0006184 GTPase activity • calcium channel regulator activity Cydrannau o'r gell • spindle midzone • cytoplasmic side of plasma membrane • Cellbilen • midbody • mitotic spindle • cnewyllyn cell • bilen Prosesau biolegol • cell surface receptor signaling pathway • metaphase plate congression • GO:0051312, GO:0007083 chromosome organization • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • GO:0072468 signal transduction • GO:0007067 Mitosis • negative regulation of high voltage-gated calcium channel activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2669	n/a
Ensembl	ENSG00000164949	n/a
UniProt	P55040	n/a
RefSeq (mRNA)	NM_181702 NM_005261	n/a
RefSeq (protein)	NP_005252 NP_859053	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GEM yw GEM a elwir hefyd yn GTP binding protein overexpressed in skeletal muscle (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GEM.

• KIR

Llyfryddiaeth

• "Identification of Gem as a new candidate prognostic marker in hepatocellular carcinoma. ". Pathol Res Pract. 2014. PMID 25155751.
• "Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission. ". PLoS Pathog. 2014. PMID 24586148.
• "The RGK family: a regulatory tail of small GTP-binding proteins. ". Trends Cell Biol. 2005. PMID 16242932.
• "Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavbeta interaction. ". Proc Natl Acad Sci U S A. 2010. PMID 20679232.
• "Biochemical and structural characterization of the gem GTPase.". J Biol Chem. 2007. PMID 17107948.