GCM1

GCM1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ODH
Dynodwyr
Cyfenwau	GCM1, GCMA, hGCMa, glial cells missing homolog 1, glial cells missing transcription factor 1
Dynodwyr allanol	OMIM: 603715 HomoloGene: 2702 GeneCards: GCM1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • zinc ion binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription factor binding • histone deacetylase binding • metal ion binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • transcription regulator complex • cnewyllyn cell Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • anatomical structure morphogenesis • positive regulation of syncytium formation by plasma membrane fusion • transcription by RNA polymerase II • transcription, DNA-templated • multicellular organism development • branching involved in labyrinthine layer morphogenesis • astrocyte fate commitment • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • gliogenesis • regulation of cell differentiation involved in embryonic placenta development • cell differentiation involved in embryonic placenta development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8521	n/a
Ensembl	ENSG00000137270	n/a
UniProt	Q9NP62	n/a
RefSeq (mRNA)	NM_003643	n/a
RefSeq (protein)	NP_003634	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GCM1 yw GCM1 a elwir hefyd yn Glial cells missing homolog 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p12.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GCM1.

• GCMA
• hGCMa

Llyfryddiaeth

• "Decreased placental GCM1 (glial cells missing) gene expression in pre-eclampsia. ". Placenta. 2004. PMID 15081636.
• "Genomic organization, chromosomal localization, and the complete 22 kb DNA sequence of the human GCMa/GCM1, a placenta-specific transcription factor gene. ". Biochem Biophys Res Commun. 2000. PMID 11071865.
• "PMA induces GCMa phosphorylation and alters its stability via the PKC- and ERK-dependent pathway. ". Biochem Biophys Res Commun. 2012. PMID 22206674.
• "GCM1 regulation of the expression of syncytin 2 and its cognate receptor MFSD2A in human placenta. ". Biol Reprod. 2010. PMID 20484742.
• "Complex patterns of GCM1 mRNA and protein in villous and extravillous trophoblast cells of the human placenta.". Placenta. 2004. PMID 15135239.