GBP1

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GBP1
Protein GBP1 PDB 1dg3.png
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauGBP1, guanylate binding protein 1
Dynodwyr allanolHomoloGene: 133759 GeneCards: GBP1
Patrwm RNA pattern
PBB GE GBP1 202270 at fs.png

PBB GE GBP1 202269 x at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002053

n/a

RefSeq (protein)

NP_002044

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GBP1 yw GBP1 a elwir hefyd yn Guanylate binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p22.2.[2]

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Guanylate-Binding Protein-1 protects ovarian cancer cell lines but not breast cancer cell lines from killing by paclitaxel. ". Biochem Biophys Res Commun. 2016. PMID 27590579.
  • "Tetrameric assembly of hGBP1 is crucial for both stimulated GMP formation and antiviral activity. ". Biochem J. 2016. PMID 27071416.
  • "Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii. ". Cell Microbiol. 2016. PMID 26874079.
  • "Guanylate-binding protein 1 (GBP1) promotes lymph node metastasis in human esophageal squamous cell carcinoma. ". Discov Med. 2015. PMID 26760981.
  • "Guanine nucleotide-binding protein 1 is one of the key molecules contributing to cancer cell radioresistance.". Cancer Sci. 2014. PMID 25098609.

Cyfeiriadau[golygu | golygu cod y dudalen]