GALNT2

GALNT2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2FFU, 2FFV, 4D0T, 4D0Z, 4D11, 5AJN, 5AJO, 5AJP, 5FV9
Dynodwyr
Cyfenwau	GALNT2, GalNAc-T2, polypeptide N-acetylgalactosaminyltransferase 2, CDG2T
Dynodwyr allanol	OMIM: 602274 HomoloGene: 3297 GeneCards: GALNT2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • manganese ion binding • glycosyltransferase activity • metal ion binding • GO:0001948, GO:0016582 protein binding • carbohydrate binding • polypeptide N-acetylgalactosaminyltransferase activity Cydrannau o'r gell • integral component of membrane • integral component of Golgi membrane • Golgi apparatus • bilen • Golgi membrane • extracellular region • Golgi cisterna membrane • perinuclear region of cytoplasm • Golgi stack • extracellular exosome • endoplasmic reticulum membrane Prosesau biolegol • protein O-linked glycosylation via serine • GO:0033578, GO:0033577, GO:0033575, GO:0033576 protein glycosylation • protein O-linked glycosylation via threonine • O-glycan processing • protein O-linked glycosylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2590	n/a
Ensembl	ENSG00000143641	n/a
UniProt	Q10471	n/a
RefSeq (mRNA)	NM_001291866 NM_004481	n/a
RefSeq (protein)	NP_001278795 NP_004472	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GALNT2 yw GALNT2 a elwir hefyd yn Polypeptide N-acetylgalactosaminyltransferase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q42.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GALNT2.

• GalNAc-T2

Llyfryddiaeth

• "Analysis to Estimate Genetic Variations in the Idarubicin-Resistant Derivative MOLT-3. ". Int J Mol Sci. 2016. PMID 28025493.
• "Glycomimetics Targeting Glycosyltransferases: Synthetic, Computational and Structural Studies of Less-Polar Conjugates. ". Chemistry. 2016. PMID 27071848.
• "Mucin glycosylating enzyme GALNT2 suppresses malignancy in gastric adenocarcinoma by reducing MET phosphorylation. ". Oncotarget. 2016. PMID 26848976.
• "Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels. ". Lipids Health Dis. 2016. PMID 26817450.
• "Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol.". Am J Hum Genet. 2015. PMID 26637976.