GADD45G

GADD45G
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2WAL, 3FFM
Dynodwyr
Cyfenwau	GADD45G, CR6, DDIT2, GADD45gamma, GRP17, growth arrest and DNA damage inducible gamma
Dynodwyr allanol	OMIM: 604949 HomoloGene: 21334 GeneCards: GADD45G
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cnewyllyn cell • cytoplasm Prosesau biolegol • positive regulation of JNK cascade • multicellular organism development • positive regulation of apoptotic process • response to stress • cell differentiation • positive regulation of p38MAPK cascade • GO:0097285 apoptotic process • regulation of cell cycle • positive regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10912	n/a
Ensembl	ENSG00000130222	n/a
UniProt	O95257	n/a
RefSeq (mRNA)	NM_006705	n/a
RefSeq (protein)	NP_006696	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GADD45G yw GADD45G a elwir hefyd yn Growth arrest and DNA damage inducible gamma (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GADD45G.

• CR6
• DDIT2
• GRP17
• GADD45gamma

Llyfryddiaeth

• "Decreased expression and aberrant methylation of Gadd45G is associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma. ". Clin Exp Metastasis. 2013. PMID 23793925.
• "Crystal structure of human Gadd45γ [corrected] reveals an active dimer. ". Protein Cell. 2011. PMID 22058036.
• "Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma. ". Oncotarget. 2015. PMID 26172295.
• "Possible Role of GADD45γ Methylation in Diffuse Large B-Cell Lymphoma: Does It Affect the Progression and Tissue Involvement?". Turk J Haematol. 2015. PMID 25912017.
• "Inducement of mitosis delay by cucurbitacin E, a novel tetracyclic triterpene from climbing stem of Cucumis melo L., through GADD45γ in human brain malignant glioma (GBM) 8401 cells.". Cell Death Dis. 2014. PMID 24577085.