GABBR1

GABBR1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4MQE, 4MQF, 4MR7, 4MR9, 4MRM, 4MS1, 4MS3, 4MS4, 4PAS
Dynodwyr
Cyfenwau	GABBR1, GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2, gamma-aminobutyric acid type B receptor subunit 1
Dynodwyr allanol	OMIM: 603540 HomoloGene: 1132 GeneCards: GABBR1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • G protein-coupled receptor activity • signal transducer activity • GO:0001948, GO:0016582 protein binding • G protein-coupled GABA receptor activity • G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Cydrannau o'r gell • cytoplasm • integral component of membrane • G protein-coupled receptor dimeric complex • postsynaptic membrane • cell projection • bilen • Cellbilen • synapse • integral component of plasma membrane • extracellular region • cell junction • dendrite • G protein-coupled receptor heterodimeric complex • presynaptic membrane • presynapse • Schaffer collateral - CA1 synapse • GABA-ergic synapse Prosesau biolegol • gamma-aminobutyric acid signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • GO:0072468 signal transduction • negative regulation of adenylate cyclase activity • G protein-coupled receptor signaling pathway • regulation of postsynaptic membrane potential • neuron-glial cell signaling Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2550	n/a
Ensembl	ENSG00000237112 ENSG00000206511 ENSG00000206466 ENSG00000232632 ENSG00000232569 ENSG00000237051 ENSG00000204681	n/a
UniProt	Q9UBS5	n/a
RefSeq (mRNA)	NM_001470 NM_021903 NM_021904 NM_021905 NM_001319053	n/a
RefSeq (protein)	NP_001305982 NP_001461 NP_068703 NP_068704	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GABBR1 yw GABBR1 a elwir hefyd yn Gamma-aminobutyric acid type B receptor subunit 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GABBR1.

• GB1
• GPRC3A
• GABABR1
• GABBR1-3

Llyfryddiaeth

• "Cytoskeletal rearrangement and Src and PI-3K-dependent Akt activation control GABA(B)R-mediated chemotaxis. ". Cell Signal. 2015. PMID 25725285.
• "Alterations of GABA and glutamate-glutamine levels in premenstrual dysphoric disorder: a 3T proton magnetic resonance spectroscopy study. ". Psychiatry Res. 2015. PMID 25465316.
• "Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. ". Biol Psychiatry. 2014. PMID 24209778.
• "GABBR1 has a HERV-W LTR in its regulatory region--a possible implication for schizophrenia. ". Biol Direct. 2013. PMID 23391219.
• "GABAB-ergic motor cortex dysfunction in SSADH deficiency.". Neurology. 2012. PMID 22722631.