G6PD

G6PD
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QKI, 2BH9, 2BHL
Dynodwyr
Cyfenwau	G6PD, G6PD1, glucose-6-phosphate dehydrogenase, Glucose-6-phosphate dehydrogenase
Dynodwyr allanol	OMIM: 305900 HomoloGene: 37906 GeneCards: G6PD
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • glucose binding • GO:0001948, GO:0016582 protein binding • NADP binding • identical protein binding • oxidoreductase activity • carbohydrate binding • glucose-6-phosphate dehydrogenase activity • oxidoreductase activity, acting on CH-OH group of donors Cydrannau o'r gell • cytoplasm • cytosol • bilen • cytoplasmic side of plasma membrane • extracellular exosome • cnewyllyn cell • intracellular membrane-bounded organelle • microtubule organizing center Prosesau biolegol • NADP metabolic process • GO:1904578 response to organic cyclic compound • substantia nigra development • glutathione metabolic process • NADPH regeneration • pentose-phosphate shunt, oxidative branch • lipid metabolism • regulation of neuron apoptotic process • ribose phosphate biosynthetic process • pentose biosynthetic process • negative regulation of protein glutathionylation • pentose-phosphate shunt • glucose metabolic process • response to food • cellular response to oxidative stress • cholesterol biosynthetic process • glucose 6-phosphate metabolic process • response to ethanol • erythrocyte maturation • positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel • negative regulation of reactive oxygen species metabolic process • negative regulation of cell growth involved in cardiac muscle cell development • response to iron(III) ion • carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2539	n/a
Ensembl	ENSG00000160211	n/a
UniProt	P11413	n/a
RefSeq (mRNA)	NM_000402 NM_001042351 NM_001360016	n/a
RefSeq (protein)	NP_000393 NP_001035810 NP_001346945	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn G6PD yw G6PD a elwir hefyd yn Glucose-6-phosphate 1-dehydrogenase a Glucose-6-phosphate dehydrogenase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xq28.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn G6PD.

• G6PD1

Llyfryddiaeth

• "Prevalence, genetic variants and clinical implications of G-6-PD deficiency in Burkina Faso: a systematic review. ". BMC Med Genet. 2017. PMID 29169341.
• "Serum Soluble Transferrin Receptor Concentrations Are Elevated in Congolese Children with Glucose-6-Phosphate Dehydrogenase Variants, but Not Sickle Cell Variants or α-Thalassemia. ". J Nutr. 2017. PMID 28768839.
• "Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD MahidolVariant) versus G6PD-Normal Volunteers. ". Am J Trop Med Hyg. 2017. PMID 28749773.
• "Asian G6PD-Mahidol Reticulocytes Sustain Normal Plasmodium Vivax Development. ". J Infect Dis. 2017. PMID 28591790.
• "Glucose-6-phosphate dehydrogenase enzyme stability in filter paper dried blood spots.". Clin Biochem. 2017. PMID 28479150.