FXYD2

FXYD2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2MKV
Dynodwyr
Cyfenwau	FXYD2, ATP1G1, HOMG2, FXYD domain containing ion transport regulator 2
Dynodwyr allanol	OMIM: 601814 HomoloGene: 86992 GeneCards: FXYD2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transporter activity • ion channel activity • P-type sodium:potassium-exchanging transporter activity • sodium channel regulator activity • ion channel regulator activity Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • extracellular exosome • integral component of plasma membrane • sodium:potassium-exchanging ATPase complex • basolateral plasma membrane • intracellular membrane-bounded organelle Prosesau biolegol • regulation of cardiac conduction • sodium ion transport • sodium ion export across plasma membrane • cludo ïon • potassium ion transport • cludo transmembrane rhwng ïonau • potassium ion import across plasma membrane • establishment or maintenance of transmembrane electrochemical gradient • regulation of cell growth • regulation of cell population proliferation • regulation of sodium ion transmembrane transporter activity • GO:0015915 transport • regulation of ion transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	486	n/a
Ensembl	ENSG00000137731	n/a
UniProt	P54710	n/a
RefSeq (mRNA)	NM_021603 NM_001127489 NM_001680	n/a
RefSeq (protein)	NP_001671 NP_067614	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FXYD2 yw FXYD2 a elwir hefyd yn FXYD domain containing ion transport regulator 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FXYD2.

• HOMG2
• ATP1G1

Llyfryddiaeth

• "Recurrent FXYD2 p.Gly41Arg mutation in patients with isolated dominant hypomagnesaemia. ". Nephrol Dial Transplant. 2015. PMID 25765846.
• "Structure of the Na,K-ATPase regulatory protein FXYD2b in micelles: implications for membrane-water interfacial arginines. ". Biochim Biophys Acta. 2015. PMID 24794573.
• "FXYD2c plays a potential role in modulating Na(+)/K (+)-ATPase activity in HK-2 cells upon hypertonic challenge. ". J Membr Biol. 2014. PMID 24258619.
• "Expression of the Na+/K+-transporting ATPase gamma subunit FXYD2 in renal tumors. ". Mod Pathol. 2013. PMID 23196795.
• "Identification of a crab gill FXYD2 protein and regulation of crab microsomal Na,K-ATPase activity by mammalian FXYD2 peptide.". Biochim Biophys Acta. 2012. PMID 22588134.