FXYD1

FXYD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JO1
Dynodwyr
Cyfenwau	FXYD1, PLM, FXYD domain containing ion transport regulator 1
Dynodwyr allanol	OMIM: 602359 HomoloGene: 3691 GeneCards: FXYD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • sodium channel regulator activity • transmembrane transporter binding • ion channel activity • chloride channel activity • ion channel regulator activity Cydrannau o'r gell • integral component of membrane • bilen • integral component of plasma membrane • sodium:potassium-exchanging ATPase complex • sarcolemma • T-tubule • intercalated disc • Cellbilen • caveola • apical plasma membrane Prosesau biolegol • muscle contraction • regulation of heart contraction • positive regulation of sodium ion export across plasma membrane • cludo ïon • regulation of sodium ion transmembrane transporter activity • regulation of cardiac muscle cell membrane potential • chloride transmembrane transport • negative regulation of protein glutathionylation • potassium ion transport • sodium ion transport • chloride transport • cludo transmembrane rhwng ïonau • regulation of ion transport • regulation of cardiac conduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5348	n/a
Ensembl	ENSG00000266964	n/a
UniProt	O00168	n/a
RefSeq (mRNA)	NM_021902 NM_001278717 NM_001278718 NM_005031	n/a
RefSeq (protein)	NP_001265646 NP_001265647 NP_005022 NP_068702	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FXYD1 yw FXYD1 a elwir hefyd yn FXYD domain containing ion transport regulator 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FXYD1.

• PLM

Llyfryddiaeth

• "Phosphomimetic mutations enhance oligomerization of phospholemman and modulate its interaction with the Na/K-ATPase. ". J Biol Chem. 2011. PMID 21220422.
• "A study of the membrane association and regulatory effect of the phospholemman cytoplasmic domain. ". Biochim Biophys Acta. 2011. PMID 21130070.
• "Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase. ". J Biol Chem. 2015. PMID 26429909.
• "Novel regulation of cardiac Na pump via phospholemman. ". J Mol Cell Cardiol. 2013. PMID 23672825.
• "Influence of chronic and acute spinal cord injury on skeletal muscle Na+-K+-ATPase and phospholemman expression in humans.". Am J Physiol Endocrinol Metab. 2012. PMID 22275761.