FUBP1

FUBP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1J4W, 2KXH, 4LIJ
Dynodwyr
Cyfenwau	FUBP1, FBP, FUBP, hDH V, far upstream element binding protein 1
Dynodwyr allanol	OMIM: 603444 HomoloGene: 48253 GeneCards: FUBP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • nucleic acid binding • single-stranded DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • RNA binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm Prosesau biolegol • GO:1901313 positive regulation of gene expression • GO:0009373 regulation of transcription, DNA-templated • transcription by RNA polymerase II • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8880	n/a
Ensembl	ENSG00000162613	n/a
UniProt	Q96AE4	n/a
RefSeq (mRNA)	NM_001303433 NM_003902 NM_001376055 NM_001376056 NM_001376057	n/a
RefSeq (protein)	NP_001290362 NP_003893 NP_001362984 NP_001362985 NP_001362986	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FUBP1 yw FUBP1 a elwir hefyd yn Far upstream element binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FUBP1.

• FBP
• FUBP
• hDH*V

Llyfryddiaeth

• "Far upstream element-binding protein 1 (FUBP1) is overexpressed in human gastric cancer tissue compared to non-cancerous tissue. ". Onkologie. 2013. PMID 24192769.
• "Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity. ". Neuropathol Appl Neurobiol. 2014. PMID 24117486.
• "Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE. ". Biochem Pharmacol. 2017. PMID 29031818.
• "Upregulation of Far Upstream Element-Binding Protein 1 (FUBP1) Promotes Tumor Proliferation and Tumorigenesis of Clear Cell Renal Cell Carcinoma. ". PLoS One. 2017. PMID 28076379.
• "Expression of far upstream element binding protein 1 in B‑cell non‑Hodgkin lymphoma is correlated with tumor growth and cell‑adhesion mediated drug resistance.". Mol Med Rep. 2016. PMID 27599538.