FSHR

FSHR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XWD, 4AY9, 4MQW
Dynodwyr
Cyfenwau	FSHR, FSHR1, FSHRO, LGR1, ODG1, follicle stimulating hormone receptor
Dynodwyr allanol	OMIM: 136435 HomoloGene: 117 GeneCards: FSHR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • G protein-coupled peptide receptor activity • G protein-coupled receptor activity • signal transducer activity • protein-hormone receptor activity • GO:0001948, GO:0016582 protein binding • follicle-stimulating hormone receptor activity Cydrannau o'r gell • integral component of membrane • bilen • integral component of plasma membrane • Cellbilen • intracellular anatomical structure • receptor complex Prosesau biolegol • G protein-coupled receptor signaling pathway • male gonad development • adenylate cyclase-activating G protein-coupled receptor signaling pathway • female gamete generation • primary ovarian follicle growth • regulation of protein kinase A signaling • female gonad development • activation of adenylate cyclase activity • regulation of osteoclast differentiation • spermatogenesis • hormone-mediated signaling pathway • positive regulation of ERK1 and ERK2 cascade • positive regulation of phosphatidylinositol 3-kinase signaling • gonad development • GO:0072468 signal transduction • positive regulation of adenylate cyclase activity • cellular response to follicle-stimulating hormone stimulus • follicle-stimulating hormone signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2492	n/a
Ensembl	ENSG00000170820	n/a
UniProt	P23945	n/a
RefSeq (mRNA)	NM_000145 NM_181446	n/a
RefSeq (protein)	NP_000136 NP_852111	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FSHR yw FSHR a elwir hefyd yn Follicle stimulating hormone receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p16.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FSHR.

• LGR1
• ODG1
• FSHR1
• FSHRO

Llyfryddiaeth

• "A novel homozygous mutation in the FSHR gene is causative for primary ovarian insufficiency. ". Fertil Steril. 2017. PMID 29157895.
• "[Study of two Chinese families affected with resistant ovarian syndrome resulted from novel mutations of FSHR gene]. ". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2017. PMID 28397217.
• "Functional characterization of two naturally occurring mutations V221G and T449N in the follicle stimulating hormone receptor. ". Mol Cell Endocrinol. 2017. PMID 27889471.
• "The carriers of the A/G-G/G allelic combination of the c.2039 A>G and c.-29 G>A FSH receptor polymorphisms retrieve the highest number of oocytes in IVF/ICSI cycles. ". J Assist Reprod Genet. 2017. PMID 27817039.
• "Association of a promoter polymorphism in FSHR with ovarian reserve and response to ovarian stimulation in women undergoing assisted reproductive treatment.". Reprod Biomed Online. 2016. PMID 27448492.