FSHB

FSHB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FL7, 1XWD, 4AY9, 4MQW
Dynodwyr
Cyfenwau	FSHB, HH24, follicle stimulating hormone beta subunit, Follitropin subunit beta, follicle stimulating hormone subunit beta
Dynodwyr allanol	OMIM: 136530 HomoloGene: 430 GeneCards: FSHB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • follicle-stimulating hormone activity • GO:0001948, GO:0016582 protein binding • hormone activity Cydrannau o'r gell • cytoplasm • extracellular region • extracellular space • follicle-stimulating hormone complex Prosesau biolegol • progesterone biosynthetic process • female gamete generation • positive regulation of bone resorption • regulation of osteoclast differentiation • transforming growth factor beta receptor signaling pathway • positive regulation of cell migration • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • female pregnancy • positive regulation of cell population proliferation • ovarian follicle development • Sertoli cell proliferation • GO:0072468 signal transduction • peptide hormone processing • GO:1901313 positive regulation of gene expression • cell-cell signaling • hormone-mediated signaling pathway • follicle-stimulating hormone signaling pathway • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • positive regulation of steroid biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2488	n/a
Ensembl	ENSG00000131808	n/a
UniProt	P01225	n/a
RefSeq (mRNA)	NM_000510 NM_001018080 NM_001382289	n/a
RefSeq (protein)	NP_000501 NP_001018090 NP_001369218	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FSHB yw FSHB a elwir hefyd yn Follicle stimulating hormone beta subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11p14.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FSHB.

• HH24

Llyfryddiaeth

• "Novel FSHβ mutation in a male patient with isolated FSH deficiency and infertility. ". Eur J Med Genet. 2017. PMID 28392474.
• "High Serum FSH is Associated with Brown Oocyte Formation and a Lower Pregnacy Rate in Human IVF Parctice. ". Cell Physiol Biochem. 2016. PMID 27442586.
• "Variants in FSHB Are Associated With Polycystic Ovary Syndrome and Luteinizing Hormone Level in Han Chinese Women. ". J Clin Endocrinol Metab. 2016. PMID 26938199.
• "The FSHB -211G>T variant attenuates serum FSH levels in the supraphysiological gonadotropin setting of Klinefelter syndrome. ". Eur J Hum Genet. 2015. PMID 25052309.
• "Effects of the FSH-β-subunit promoter polymorphism -211G->T on the hypothalamic-pituitary-ovarian axis in normally cycling women indicate a gender-specific regulation of gonadotropin secretion.". J Clin Endocrinol Metab. 2013. PMID 23118424.