FOXK1 Dynodwyr Cyfenwau FOXK1 Dynodwyr allanol OMIM: 616302 HomoloGene: 82414 GeneCards: FOXK1 Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0000975 transcription cis-regulatory region binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • cytoplasm Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • multicellular organism development • muscle organ development • GO:0045996 negative regulation of transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • protein deubiquitination • anatomical structure morphogenesis • cell differentiation • GO:1901227 negative regulation of transcription by RNA polymerase II • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn FOXK1 yw FOXK1 a elwir hefyd yn Forkhead box K1 (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p22.1.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FOXK1.
"Identification and characterization of a novel human FOXK1 gene in silico. ". Int J Oncol . 2004. PMID 15289879 . "Direct regulation of FOXK1 by C-jun promotes proliferation, invasion and metastasis in gastric cancer cells. ". Cell Death Dis . 2016. PMID 27882939 . "FOXK1 plays an oncogenic role in the development of esophageal cancer. ". Biochem Biophys Res Commun . 2017. PMID 29050933 . "Knockdown of FOXK1 alone or in combination with apoptosis-inducing 5-FU inhibits cell growth in colorectal cancer. ". Oncol Rep . 2016. PMID 27571921 . "Forkhead box protein k1 recruits TET1 to act as a tumor suppressor and is associated with MRI detection. ". Jpn J Clin Oncol . 2016. PMID 26732382 . 
