FOLH1

FOLH1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4P4J, 1Z8L, 2C6C, 2C6G, 2C6P, 2CIJ, 2JBJ, 2JBK, 2OOT, 2OR4, 2PVV, 2PVW, 2XEF, 2XEG, 2XEI, 2XEJ, 3BHX, 3BI0, 3BI1, 3BXM, 3D7D, 3D7F, 3D7G, 3D7H, 3IWW, 3RBU, 3SJE, 3SJF, 3SJG, 3SJX, 4JYW, 4JZ0, 4LQG, 4MCP, 4MCQ, 4MCR, 4MCS, 4NGM, 4NGN, 4NGP, 4NGQ, 4NGR, 4NGS, 4NGT, 4OC0, 4OC1, 4OC2, 4OC3, 4OC4, 4OC5, 4OME, 4P44, 4P45, 4P4B, 4P4D, 4P4E, 4P4F, 4P4I, 4W9Y, 4X3R, 5F09, 5D29, 5ELY
Dynodwyr
Cyfenwau	FOLH1, FGCP, FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA, mGCP, folate hydrolase (prostate-specific membrane antigen) 1, folate hydrolase 1
Dynodwyr allanol	OMIM: 600934 HomoloGene: 136782 GeneCards: FOLH1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • tetrahydrofolyl-poly(glutamate) polymer binding • GO:0070122 peptidase activity • catalytic activity • metallocarboxypeptidase activity • carboxypeptidase activity • Ac-Asp-Glu binding • hydrolase activity • metallopeptidase activity • dipeptidase activity Cydrannau o'r gell • cytoplasm • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • cell surface • extracellular exosome Prosesau biolegol • cellular amino acid biosynthetic process • proteolysis • C-terminal protein deglutamylation • metabolaeth • folic acid-containing compound metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2346	n/a
Ensembl	ENSG00000086205	n/a
UniProt	Q04609	n/a
RefSeq (mRNA)	NM_001014986 NM_001193471 NM_001193472 NM_001193473 NM_004476 NM_001351236	n/a
RefSeq (protein)	NP_001014986 NP_001180400 NP_001180401 NP_001180402 NP_004467 NP_001338165	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FOLH1 yw FOLH1 a elwir hefyd yn Glutamate carboxypeptidase 2 a Folate hydrolase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p11.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FOLH1.

• PSM
• FGCP
• FOLH
• GCP2
• PSMA
• mGCP
• GCPII
• NAALAD1
• NAALAdase

Llyfryddiaeth

• "Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry. ". PLoS One. 2017. PMID 28472168.
• "Prostate-specific membrane antigen-directed nanoparticle targeting for extreme nearfield ablation of prostate cancer cells. ". Tumour Biol. 2017. PMID 28351335.
• "Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging. ". Oncotarget. 2017. PMID 28051996.
• "Evaluation of 68Ga-Glutamate Carboxypeptidase II Ligand Positron Emission Tomography for Clinical Molecular Imaging of Atherosclerotic Plaque Neovascularization. ". Arterioscler Thromb Vasc Biol. 2016. PMID 27609368.
• "[Domestication of suspension CHO cells and its application in the expression of anti-PSMA antibody].". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2016. PMID 27358992.