FHL1

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FHL1
Protein FHL1 PDB 1x63.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauFHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA, RBMX1A, RBMX1B, four and a half LIM domains 1, FCMSU
Dynodwyr allanolOMIM: 300163 MGI: 1298387 HomoloGene: 31038 GeneCards: FHL1
Patrwm RNA pattern
PBB GE FHL1 201539 s at fs.png

PBB GE FHL1 210298 x at fs.png

PBB GE FHL1 201540 at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001077361
NM_001077362
NM_001287800
NM_010211

RefSeq (protein)

NP_001070829
NP_001070830
NP_001274729
NP_034341

Lleoliad (UCSC)n/aChr : 56.73 – 56.79 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn FHL1 yw FHL1 a elwir hefyd yn Four and a half LIM domains protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq26.3.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FHL1.

  • KYOT
  • SLIM
  • FCMSU
  • FHL-1
  • FHL1A
  • FHL1B
  • FLH1A
  • SLIM1
  • XMPMA
  • RBMX1A
  • RBMX1B
  • SLIM-1
  • SLIMMER

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac Death. ". Circ Cardiovasc Genet. 2016. PMID 26933038.
  • "X-linked FHL1 as a novel therapeutic target for head and neck squamous cell carcinoma. ". Oncotarget. 2016. PMID 26908444.
  • "Unclassifiable arrhythmic cardiomyopathy associated with Emery-Dreifuss caused by a mutation in FHL1. ". Clin Genet. 2016. PMID 26857240.
  • "Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies. ". J Clin Invest. 2015. PMID 26551678.
  • "[FHL1 knockdown mediated by lentiviral shRNA promotes the growth of HeLa and HepG2 cells].". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2015. PMID 26146054.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. 1.0 1.1 1.2 GRCm38: Ensembl release 89: ENSMUSG00000023092 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. FHL1 - Cronfa NCBI