FCN3

FCN3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2J5Z, 2J60, 2J64
Dynodwyr
Cyfenwau	FCN3, FCNH, HAKA1, ficolin 3
Dynodwyr allanol	OMIM: 604973 HomoloGene: 130523 GeneCards: FCN3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0003823, GO:0051635 antigen binding • GO:0001948, GO:0016582 protein binding • metal ion binding • carbohydrate binding • serine-type endopeptidase activity Cydrannau o'r gell • extracellular region • collagen • blood microparticle Prosesau biolegol • complement activation, lectin pathway • complement activation • recognition of apoptotic cell • negative regulation of RNA biosynthetic process • immune system process • innate immune response • proteolysis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8547	n/a
Ensembl	ENSG00000142748	n/a
UniProt	O75636	n/a
RefSeq (mRNA)	NM_003665 NM_173452	n/a
RefSeq (protein)	NP_003656 NP_775628	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FCN3 yw FCN3 a elwir hefyd yn Ficolin 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FCN3.

• FCNH
• HAKA1

Llyfryddiaeth

• "Low serum ficolin-3 levels are associated with severity and poor outcome in traumatic brain injury. ". J Neuroinflammation. 2015. PMID 26627059.
• "H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses. ". Immunology. 2015. PMID 26133042.
• "Association of a new FCN3 haplotype with high ficolin-3 levels in leprosy. ". PLoS Negl Trop Dis. 2017. PMID 28241035.
• "Association between the Presence of Autoantibodies Targeting Ficolin-3 and Active Nephritis in Patients with Systemic Lupus Erythematosus. ". PLoS One. 2016. PMID 27631981.
• "Alveolar recruitment of ficolin-3 in response to acute pulmonary inflammation in humans.". Immunobiology. 2016. PMID 26868430.