FCN2

FCN2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2J0G, 2J0H, 2J0Y, 2J1G, 2J2P, 2J3F, 2J3G, 2J3O, 2J3U, 2J61, 4NYT, 4R9J, 4R9T
Dynodwyr
Cyfenwau	FCN2, EBP-37, FCNL, P35, ficolin-2, ficolin 2
Dynodwyr allanol	OMIM: 601624 HomoloGene: 3031 GeneCards: FCN2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0003823, GO:0051635 antigen binding • GO:0001948, GO:0016582 protein binding • mannan binding • metal ion binding • calcium-dependent protein binding • carbohydrate binding • proteoglycan binding • serine-type endopeptidase activity Cydrannau o'r gell • extracellular region • collagen • blood microparticle • extracellular exosome Prosesau biolegol • immune system process • complement activation, lectin pathway • complement activation • recognition of apoptotic cell • opsonization • GO:0051637 defense response to Gram-positive bacterium • innate immune response • proteolysis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2220	n/a
Ensembl	n/a	n/a
UniProt	Q15485	n/a
RefSeq (mRNA)	NM_004108 NM_015837 NM_015838 NM_015839	n/a
RefSeq (protein)	NP_004099 NP_056652	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FCN2 yw FCN2 a elwir hefyd yn Ficolin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q34.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FCN2.

• P35
• FCNL
• EBP-37
• ficolin-2

Llyfryddiaeth

• "The prevalence of the variants of the L-ficolin gene (FCN2) in the arctic populations of East Siberia. ". Immunogenetics. 2017. PMID 28391359.
• "FCN2 c.772G>T polymorphism is associated with chronic adenoiditis and/or tonsillitis, but not -4 A>G and -602 G>A. ". Int J Pediatr Otorhinolaryngol. 2016. PMID 27368434.
• "The Lectin Complement Pathway in Patients with Necrotizing Soft Tissue Infection. ". J Innate Immun. 2016. PMID 27355483.
• "Ficolin Gene Polymorphisms in Systemic Lupus Erythematosus and Rheumatoid Arthritis. ". Ann Hum Genet. 2016. PMID 26464189.
• "Association of the FCN2 Gene Single Nucleotide Polymorphisms with Susceptibility to Pulmonary Tuberculosis.". PLoS One. 2015. PMID 26379154.