Neidio i'r cynnwys

FCGRT

Oddi ar Wicipedia
FCGRT
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauFCGRT, FCRN, alpha-chain, Fc fragment of IgG receptor and transporter, FcgammaRn, Fc gamma receptor and transporter
Dynodwyr allanolOMIM: 601437 HomoloGene: 3030 GeneCards: FCGRT
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136019
NM_004107

n/a

RefSeq (protein)

NP_001129491
NP_004098

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FCGRT yw FCGRT a elwir hefyd yn IgG receptor FcRn large subunit p51 a Fc fragment of IgG receptor and transporter (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.33.[2]

Cyfystyron

[golygu | golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FCGRT.

  • FCRN
  • alpha-chain

Llyfryddiaeth

[golygu | golygu cod]
  • "Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin. ". PLoS Med. 2017. PMID 28991911.
  • "The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa. ". J Immunol. 2017. PMID 28760885.
  • "Correlation of FCGRT genomic structure with serum immunoglobulin, albumin and farletuzumab pharmacokinetics in patients with first relapsed ovarian cancer. ". Genomics. 2017. PMID 28450240.
  • "The expression and function of the neonatal Fc receptor in thyrocytes of Hashimoto's thyroiditis. ". Int Immunopharmacol. 2017. PMID 28081504.
  • "Neonatal Fc receptor FcRn is involved in intracellular transport of the Fc fusion protein aflibercept and its transition through retinal endothelial cells.". Exp Eye Res. 2017. PMID 27836572.

Cyfeiriadau

[golygu | golygu cod]
  1. "Human PubMed Reference:".
  2. FCGRT - Cronfa NCBI