FCGR2A

FCGR2A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FCG, 1H9V, 3D5O, 3RY4, 3RY5, 3RY6
Dynodwyr
Cyfenwau	FCGR2A, CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2, Fc fragment of IgG receptor IIa, FcgammaRIIa, Fc gamma receptor IIa
Dynodwyr allanol	OMIM: 146790 HomoloGene: 47936 GeneCards: FCGR2A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • IgG binding Cydrannau o'r gell • integral component of membrane • Cellbilen • bilen • secretory granule membrane • Cellfur Prosesau biolegol • Fc-gamma receptor signaling pathway involved in phagocytosis • immune system process • neutrophil degranulation • cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2212	n/a
Ensembl	ENSG00000143226	n/a
UniProt	P12318	n/a
RefSeq (mRNA)	NM_001136219 NM_021642 NM_001375296 NM_001375297	n/a
RefSeq (protein)	NP_001129691 NP_067674 NP_001362225 NP_001362226	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FCGR2A yw FCGR2A a elwir hefyd yn Low affinity immunoglobulin gamma Fc region receptor II-a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FCGR2A.

• CD32
• FCG2
• FcGR
• CD32A
• CDw32
• FCGR2
• IGFR2
• FCGR2A1

Llyfryddiaeth

• "Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases. ". J Clin Invest. 2017. PMID 28891817.
• "Male-specific association of the FCGR2A His167Arg polymorphism with Kawasaki disease. ". PLoS One. 2017. PMID 28886140.
• "CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses. ". Nature. 2017. PMID 28297712.
• "FcγRIIa-H131R variant is associated with inferior response in diffuse large B cell lymphoma: A meta-analysis of genetic risk. ". J BUON. 2016. PMID 28039707.
• "[Analysis of single nucleotide polymorphisms and haplotypes of FCGR2A gene among patients with ulcerative colitis].". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2016. PMID 27984611.