FBXO2

FBXO2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UMH, 1UMI, 2E31, 2E32, 2E33, 2RJ2
Dynodwyr
Cyfenwau	FBXO2, FBG1, FBX2, Fbs1, NFB42, OCP1, F-box protein 2
Dynodwyr allanol	OMIM: 607112 HomoloGene: 8132 GeneCards: FBXO2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • amyloid-beta binding • carbohydrate binding • GO:0050372 ubiquitin-protein transferase activity • GO:0001948, GO:0016582 protein binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity Cydrannau o'r gell • organelle membrane • bilen • SCF ubiquitin ligase complex • intracellular membrane-bounded organelle • dendritic spine • Reticwlwm endoplasmig • cytosol • cytoplasm Prosesau biolegol • ubiquitin-dependent protein catabolic process • regulation of protein ubiquitination • proteolysis • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • protein ubiquitination • ubiquitin-dependent ERAD pathway • glycoprotein catabolic process • negative regulation of cell population proliferation • protein polyubiquitination • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	26232	n/a
Ensembl	ENSG00000116661	n/a
UniProt	Q9UK22	n/a
RefSeq (mRNA)	NM_012168	n/a
RefSeq (protein)	NP_036300	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FBXO2 yw FBXO2 a elwir hefyd yn F-box protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.22.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FBXO2.

• FBG1
• FBX2
• Fbs1
• OCP1
• NFB42

Llyfryddiaeth

• "Energetics of OCP1-OCP2 complex formation. ". Biophys Chem. 2008. PMID 18284940.
• "The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3. ". PLoS One. 2015. PMID 26460611.
• "Replication-initiator protein (UL9) of the herpes simplex virus 1 binds NFB42 and is degraded via the ubiquitin-proteasome pathway. ". Proc Natl Acad Sci U S A. 2003. PMID 12904574.
• "Organ of Corti-specific polypeptides: OCP-I and OCP-II. ". Arch Otorhinolaryngol. 1980. PMID 7458746.
• "Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase.". Acta Crystallogr F Struct Biol Commun. 2016. PMID 27487926.