FASN

fatty acid synthase
Dynodwyr
Cyfenwau	fatty acid synthases
Dynodwyr allanol	GeneCards: [1]
Orthologau
Species	Bod dynol	Llygoden
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FASN yw FASN a elwir hefyd yn Fatty acid synthase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FASN.

• FAS
• OA-519
• SDR27X1

Llyfryddiaeth

• "Inhibition of FASN suppresses migration, invasion and growth in hepatoma carcinoma cells by deregulating the HIF-1α/IGFBP1 pathway. ". Int J Oncol. 2017. PMID 28197637.
• "FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression. ". EBioMedicine. 2017. PMID 28159572.
• "Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model. ". Lab Invest. 2017. PMID 27918556.
• "Inhibition of fatty acid synthase suppresses neovascularization via regulating the expression of VEGF-A in glioma. ". J Cancer Res Clin Oncol. 2016. PMID 27601165.
• "FASN, dietary fat intake, and risk of uterine leiomyomata in the Black Women's Health Study.". Fertil Steril. 2016. PMID 27375065.