FABP1

FABP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2F73, 2L67, 2L68, 2LKK, 2PY1, 3B2H, 3B2I, 3B2J, 3B2K, 3B2L, 3STK, 3STM, 3STN, 3VG2, 3VG3, 3VG4, 3VG5, 3VG6, 3VG7
Dynodwyr
Cyfenwau	FABP1, FABPL, L-FABP, fatty acid binding protein 1
Dynodwyr allanol	OMIM: 134650 HomoloGene: 1106 GeneCards: FABP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0005325 long-chain fatty acid transporter activity • transporter activity • chromatin binding • fatty acid binding • bile acid binding • antioxidant activity • GO:0001948, GO:0016582 protein binding • phospholipid binding • lipid binding Cydrannau o'r gell • nucleoplasm • apical cortex • peroxisomal matrix • extracellular exosome • cnewyllyn cell • cytoplasm • cytosol • GO:0009327 protein-containing complex Prosesau biolegol • positive regulation of fatty acid beta-oxidation • positive regulation of hydrolase activity • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • negative regulation of apoptotic process • triglyceride catabolic process • positive regulation of cell population proliferation • intestinal absorption • cellular response to hypoxia • cellular response to hydrogen peroxide • long-chain fatty acid transport • cellular oxidant detoxification • regulation of lipid metabolic process • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2168	n/a
Ensembl	ENSG00000163586	n/a
UniProt	P07148	n/a
RefSeq (mRNA)	NM_001443	n/a
RefSeq (protein)	NP_001434	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FABP1 yw FABP1 a elwir hefyd yn Fatty acid binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FABP1.

• FABPL
• L-FABP

Llyfryddiaeth

• "Molecular differences between human liver fatty acid binding protein and its T94A variant in their unbound and lipid-bound states. ". Biochim Biophys Acta. 2017. PMID 28668637.
• "Effects of macromolecular crowding on a small lipid binding protein probed at the single-amino acid level. ". Arch Biochem Biophys. 2016. PMID 27457417.
• "Expression of liver fatty acid binding protein in hepatocellular carcinoma. ". Hum Pathol. 2016. PMID 26997447.
• "Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma. ". Oncotarget. 2016. PMID 26919097.
• "Association of single-nucleotide polymorphisms rs2197076 and rs2241883 of FABP1 gene with polycystic ovary syndrome.". J Assist Reprod Genet. 2016. PMID 26650609.