F9

F9
Strwythurau PDB Orthologau:PDBe RCSB Rhestr o ddynodwyr PDB 1CFH, 1CFI, 1EDM, 1IXA, 1MGX, 1NL0, 1RFN, 2WPH, 2WPI, 2WPJ, 2WPK, 2WPL, 2WPM, 3KCG, 3LC3, 3LC5, 4YZU, 4Z0K, 4ZAE, 4WM0, 4WMA, 4WMI, 4WMK, 4WN2, 4WNH, 5EGM, 5JBC, 5JB9, 5JBB, 5JB8, 5JBA
Dynodwyr
Cyfenwau	F9, F9 p22, FIX, HEMB, P19, PTC, THPH8, coagulation factor IX, Blood coagulation factor IX, Christmas Factor
Dynodwyr allanol	OMIM: 300746 MGI: 88384 HomoloGene: 106 GeneCards: F9
Lleoliad y genyn (llygoedn) Cr. Cromosom X (llygoden) Band X A6|X 33.5 cM Start 59,999,464 bp End 60,030,759 bp
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • metal ion binding • peptidase activity • serine-type peptidase activity • hydrolase activity • calcium ion binding • serine-type endopeptidase activity • protein binding Cydrannau o'r gell • endoplasmic reticulum lumen • Cellbilen • Golgi lumen • extracellular exosome • extracellular region • extracellular space • collagen-containing extracellular matrix Prosesau biolegol • hemostasis • blood coagulation, intrinsic pathway • zymogen activation • ER to Golgi vesicle-mediated transport • signal peptide processing • blood coagulation, extrinsic pathway • peptidyl-glutamic acid carboxylation • proteolysis • blood coagulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2158	14071
Ensembl	ENSG00000101981	ENSMUSG00000031138
UniProt	P00740	P16294
RefSeq (mRNA)	NM_000133 NM_001313913	NM_007979 NM_001305797
RefSeq (protein)	NP_000124 NP_001300842	NP_001292726 NP_032005
Lleoliad (UCSC)	n/a	Chr : 60 – 60.03 Mb
PubMed search
Wicidata
Gweld/Golygu Bod dynol Gweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn F9 yw F9 a elwir hefyd yn Coagulation factor IX (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq27.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F9.

• FIX
• P19
• PTC
• HEMB
• THPH8
• F9*p22

Llyfryddiaeth

• "Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations. ". Blood. 2017. PMID 28196793.
• "Usual and unusual mutations in a cohort of Belgian patients with hemophilia B. ". Thromb Res. 2017. PMID 27865967.
• "[Mutational Analysis of Hemophilia B in Russia: Molecular-Genetic Study]. ". Genetika. 2016. PMID 27529981.
• "Development and Optimization of AAV hFIX Particles by Transient Transfection in an iCELLis(®) Fixed-Bed Bioreactor. ". Hum Gene Ther Methods. 2016. PMID 27229773.
• "Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function.". PLoS Genet. 2016. PMID 27227676.