EXOSC7

EXOSC7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2NN6
Dynodwyr
Cyfenwau	EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8, Exosome component 7
Dynodwyr allanol	OMIM: 606488 HomoloGene: 8994 GeneCards: EXOSC7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • 3'-5'-exoribonuclease activity • exoribonuclease activity • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • cytoplasm • cytosol • exosome (RNase complex) • nucleolus • nucleoplasm • cnewyllyn cell • nuclear exosome (RNase complex) • cytoplasmic exosome (RNase complex) Prosesau biolegol • regulation of mRNA stability • RNA catabolic process • rRNA processing • exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' • U1 snRNA 3'-end processing • U4 snRNA 3'-end processing • U5 snRNA 3'-end processing • exonucleolytic catabolism of deadenylated mRNA • GO:0071049, GO:0071048, GO:0071033 nuclear mRNA surveillance • nuclear polyadenylation-dependent rRNA catabolic process • nuclear polyadenylation-dependent tRNA catabolic process • nuclear polyadenylation-dependent mRNA catabolic process • rRNA catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23016	n/a
Ensembl	ENSG00000075914	n/a
UniProt	Q15024	n/a
RefSeq (mRNA)	NM_015004	n/a
RefSeq (protein)	NP_055819	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EXOSC7 yw EXOSC7 a elwir hefyd yn Exosome component 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p21.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EXOSC7.

• p8
• EAP1
• RRP42
• Rrp42p
• hRrp42p

Llyfryddiaeth

• "Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation. ". Proc Natl Acad Sci U S A. 2011. PMID 21876179.
• "The association of the human PM/Scl-75 autoantigen with the exosome is dependent on a newly identified N terminus. ". J Biol Chem. 2003. PMID 12788944.
• "The yin and yang of the exosome. ". Trends Cell Biol. 2002. PMID 11849973.
• "Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA. ". Nature. 2014. PMID 25043052.
• "Autoantibodies directed to novel components of the PM/Scl complex, the human exosome.". Arthritis Res. 2002. PMID 11879549.