ESR2

ESR2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4J26, 1L2J, 1NDE, 1QKM, 1U3Q, 1U3R, 1U3S, 1U9E, 1X76, 1X78, 1X7B, 1X7J, 1YY4, 1YYE, 1ZAF, 2FSZ, 2GIU, 2I0G, 2JJ3, 2NV7, 2QTU, 2YJD, 2YLY, 2Z4B, 3OLL, 3OLS, 3OMO, 3OMP, 3OMQ, 4J24, 4ZI1
Dynodwyr
Cyfenwau	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, estrogen receptor 2, ODG8
Dynodwyr allanol	OMIM: 601663 HomoloGene: 1100 GeneCards: ESR2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity • metal ion binding • steroid hormone receptor activity • steroid binding • zinc ion binding • GO:0001948, GO:0016582 protein binding • DNA binding • sequence-specific DNA binding • GO:0001105 transcription coactivator activity • receptor antagonist activity • lipid binding • enzyme binding • estrogen response element binding • core promoter sequence-specific DNA binding • estrogen receptor activity • identical protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding Cydrannau o'r gell • mitocondria • cnewyllyn cell • nucleoplasm • extracellular region Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • negative regulation of cell growth • transcription initiation from RNA polymerase II promoter • positive regulation of DNA-binding transcription factor activity • cell-cell signaling • GO:0072468 signal transduction • extracellular negative regulation of signal transduction • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • intracellular estrogen receptor signaling pathway • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • cellular response to estradiol stimulus • negative regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2100	n/a
Ensembl	ENSG00000140009	n/a
UniProt	Q92731	n/a
RefSeq (mRNA)	NM_001040275 NM_001040276 NM_001214902 NM_001214903 NM_001271876 NM_001271877 NM_001291712 NM_001291723 NM_001437	n/a
RefSeq (protein)	NP_001035365 NP_001201831 NP_001258805 NP_001258806 NP_001278641 NP_001278652 NP_001428	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ESR2 yw ESR2 a elwir hefyd yn Estrogen receptor 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q23.2-q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ESR2.

• Erb
• ESRB
• ESTRB
• NR3A2
• ER-BETA
• ESR-BETA

Llyfryddiaeth

• "Oestrogen receptor β (ERβ) regulates osteogenic differentiation of human dental pulp cells. ". J Steroid Biochem Mol Biol. 2017. PMID 29031686.
• "The Association of Estrogen Receptor-β Gene Variation With Salt-Sensitive Blood Pressure. ". J Clin Endocrinol Metab. 2017. PMID 28938457.
• "ESR2 Genetic Variants and Combined Oral Contraceptive Use Associated with the Risk of Stroke. ". Arch Med Res. 2017. PMID 28625324.
• "Interaction of estrogen receptor β and negative life events in susceptibility to major depressive disorder in a Chinese Han female population. ". J Affect Disord. 2017. PMID 27814959.
• "Estrogen receptor β in Merkel cell carcinoma: its possible roles in pathogenesis.". Hum Pathol. 2016. PMID 27343835.