ERP29

ERP29
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2QC7
Dynodwyr
Cyfenwau	ERP29, C12orf8, ERp28, ERp31, HEL-S-107, PDI-DB, PDIA9, endoplasmic reticulum protein 29
Dynodwyr allanol	OMIM: 602287 HomoloGene: 4963 GeneCards: ERP29
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chaperone binding • protein homodimerization activity • GO:0030508 protein disulfide isomerase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • endoplasmic reticulum lumen • bilen • melanosome • transport vesicle • smooth endoplasmic reticulum • cell surface • Reticwlwm endoplasmig • extracellular exosome Prosesau biolegol • positive regulation of protein phosphorylation • regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway • negative regulation of gene expression • protein secretion • GO:1901313 positive regulation of gene expression • protein unfolding • intracellular protein transport • negative regulation of protein secretion • protein folding Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10961	n/a
Ensembl	ENSG00000089248	n/a
UniProt	P30040	n/a
RefSeq (mRNA)	NM_006817 NM_001034025	n/a
RefSeq (protein)	NP_001029197 NP_006808	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ERP29 yw ERP29 a elwir hefyd yn Endoplasmic reticulum protein 29 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q24.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ERP29.

• ERp28
• ERp31
• PDIA9
• PDI-DB
• C12orf8
• HEL-S-107

Llyfryddiaeth

• "Identification of ERp29 as a biomarker for predicting nasopharyngeal carcinoma response to radiotherapy. ". Oncol Rep. 2012. PMID 22160175.
• "Inhibiting ERp29 expression enhances radiosensitivity in human nasopharyngeal carcinoma cell lines. ". Med Oncol. 2012. PMID 21479953.
• "Erp29 Attenuates Cigarette Smoke Extract-Induced Endoplasmic Reticulum Stress and Mitigates Tight Junction Damage in Retinal Pigment Epithelial Cells. ". Invest Ophthalmol Vis Sci. 2015. PMID 26431474.
• "ERp29 regulates epithelial sodium channel functional expression by promoting channel cleavage. ". Am J Physiol Cell Physiol. 2014. PMID 24944201.
• "Endoplasmic reticulum protein 29 regulates epithelial cell integrity during the mesenchymal-epithelial transition in breast cancer cells.". Oncogene. 2013. PMID 22543584.