ERCC1

Oddi ar Wicipedia
Jump to navigation Jump to search
ERCC1
Protein ERCC1 PDB 1z00.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauERCC1, COFS4, RAD10, UV20, excision repair cross-complementation group 1, ERCC excision repair 1, endonuclease non-catalytic subunit
Dynodwyr allanolOMIM: 126380 MGI: 95412 HomoloGene: 1501 GeneCards: ERCC1
Patrwm RNA pattern
PBB GE ERCC1 203720 s at fs.png

PBB GE ERCC1 203719 at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001166049
NM_001983
NM_202001

NM_001127324
NM_007948

RefSeq (protein)

NP_001120796
NP_031974

Lleoliad (UCSC)n/aChr : 19.34 – 19.36 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn ERCC1 yw ERCC1 a elwir hefyd yn DNA excision repair protein ERCC-1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.32.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ERCC1.

  • UV20
  • COFS4
  • RAD10

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Association between the ERCC1 polymorphism and platinum-based chemotherapy effectiveness in ovarian cancer: a meta-analysis. ". BMC Womens Health. 2017. PMID 28623887.
  • "The Contribution of Excision Repair Cross-complementing Group 1 Genotypes to Colorectal Cancer Susceptibility in Taiwan. ". Anticancer Res. 2017. PMID 28476796.
  • "Chemosensitizing effect of shRNA-mediated ERCC1 silencing on a Xuanwei lung adenocarcinoma cell line and its clinical significance. ". Oncol Rep. 2017. PMID 28260069.
  • "Computed Tomography Manifestations and Excision Cross-Complementation Group 1 Expression of Stage I Non-Small-Cell Lung Cancer and Their Correlation With Prognosis. ". J Comput Assist Tomogr. 2016. PMID 27434787.
  • "ERCC1 C118T polymorphism has predictive value for platinum-based chemotherapy in patients with late-stage bladder cancer.". Genet Mol Res. 2016. PMID 27323074.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. 1.0 1.1 1.2 GRCm38: Ensembl release 89: ENSMUSG00000003549 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. ERCC1 - Cronfa NCBI