ERBB3

Oddi ar Wicipedia
Jump to navigation Jump to search
ERBB3
Protein ERBB3 PDB 1m6b.png
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, erb-b2 receptor tyrosine kinase 3, FERLK
Dynodwyr allanolOMIM: 190151 HomoloGene: 20457 GeneCards: ERBB3
Patrwm RNA pattern
PBB GE ERBB3 202454 s at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001982
NM_001005915

n/a

RefSeq (protein)

NP_001005915
NP_001973

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ERBB3 yw ERBB3 a elwir hefyd yn Erb-b2 receptor tyrosine kinase 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q13.2.[2]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ERBB3.

  • HER3
  • LCCS2
  • ErbB-3
  • c-erbB3
  • erbB3-S
  • MDA-BF-1
  • c-erbB-3
  • p180-ErbB3
  • p45-sErbB3
  • p85-sErbB3

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Engineered Multivalency Enhances Affibody-Based HER3 Inhibition and Downregulation in Cancer Cells. ". Mol Pharm. 2017. PMID 28248115.
  • "Prognostic impact of HER3 based on protein and mRNA expression in high-grade serous ovarian carcinoma. ". Virchows Arch. 2017. PMID 27913862.
  • "HER3 Expression Is a Marker of Tumor Progression in Premalignant Lesions of the Gastroesophageal Junction. ". PLoS One. 2016. PMID 27559738.
  • "Integrated and Functional Genomics Analysis Validates the Relevance of the Nuclear Variant ErbB380kDa in Prostate Cancer Progression. ". PLoS One. 2016. PMID 27191720.
  • "HER3 expression is correlated to distally located and low-grade colon cancer.". Acta Oncol. 2016. PMID 26863446.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. "Human PubMed Reference:".
  2. ERBB3 - Cronfa NCBI