EPS8L2

EPS8L2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WWU, 1WXB
Dynodwyr
Cyfenwau	EPS8L2, EPS8R2, EPS8 like 2, DFNB106
Dynodwyr allanol	OMIM: 614988 HomoloGene: 69358 GeneCards: EPS8L2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin binding • cadherin binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • ruffle membrane • fesigl • Cellbilen • extracellular exosome • cytoplasm • cytosol • stereocilium bundle • stereocilium tip • stereocilium • GO:0009327 protein-containing complex • cell projection Prosesau biolegol • regulation of Rho protein signal transduction • Rho protein signal transduction • positive regulation of ruffle assembly • sensory perception of sound • regulation of molecular function Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	64787	n/a
Ensembl	ENSG00000177106	n/a
UniProt	Q9H6S3	n/a
RefSeq (mRNA)	NM_022772	n/a
RefSeq (protein)	NP_073609	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EPS8L2 yw EPS8L2 a elwir hefyd yn EPS8 like 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11p15.5.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EPS8L2.

• EPS8R2
• DFNB106

Llyfryddiaeth

• "Global phosphoproteome of HT-29 human colon adenocarcinoma cells. ". J Proteome Res. 2005. PMID 16083285.
• "Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. ". FASEB J. 2009. PMID 19190083.
• "EPS8L2 is a new causal gene for childhood onset autosomal recessive progressive hearing loss. ". Orphanet J Rare Dis. 2015. PMID 26282398.
• "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure. ". Genomics. 2003. PMID 12620401.
• "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway.". Mol Biol Cell. 2004. PMID 14565974.