EPS8

EPS8
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2E8M
Dynodwyr
Cyfenwau	EPS8, DFNB102, epidermal growth factor receptor pathway substrate 8
Dynodwyr allanol	OMIM: 600206 HomoloGene: 3272 GeneCards: EPS8
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signaling adaptor activity • GO:0001948, GO:0016582 protein binding • actin binding Cydrannau o'r gell • cytoplasm • fesigl • cell projection • bilen • GO:0097483, GO:0097481 postsynaptic density • growth cone • Cellbilen • synapse • NMDA selective glutamate receptor complex • stereocilium • ruffle membrane • cell junction • cell cortex • brush border • neuron projection • extracellular exosome • stereocilium bundle • stereocilium tip • glutamatergic synapse Prosesau biolegol • actin cytoskeleton reorganization • actin polymerization-dependent cell motility • epidermal growth factor receptor signaling pathway • regulation of actin filament length • adult locomotory behavior • barbed-end actin filament capping • exit from mitosis • actin filament bundle assembly • dendritic cell migration • actin crosslink formation • regulation of cell shape • behavioral response to ethanol • cell population proliferation • Rac protein signal transduction • GO:0072468 signal transduction • positive regulation of signal transduction • cellular response to leukemia inhibitory factor • Rho protein signal transduction • regulation of Rho protein signal transduction • regulation of postsynaptic membrane neurotransmitter receptor levels • positive regulation of ruffle assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2059	n/a
Ensembl	ENSG00000151491	n/a
UniProt	Q12929	n/a
RefSeq (mRNA)	NM_004447	n/a
RefSeq (protein)	NP_004438	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EPS8 yw EPS8 a elwir hefyd yn Epidermal growth factor receptor kinase substrate 8 ac Epidermal growth factor receptor pathway substrate 8 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12p12.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EPS8.

• DFNB102

Llyfryddiaeth

• "Epidermal growth factor receptor kinase substrate 8 promotes the metastasis of cervical cancer via the epithelial-mesenchymal transition. ". Mol Med Rep. 2016. PMID 27573546.
• "Overexpression of EPS8 is associated with poor prognosis in patients with acute lymphoblastic leukemia. ". Leuk Res. 2015. PMID 25843487.
• "Generation of cytotoxic T lymphocytes specific for native or modified peptides derived from the epidermal growth factor receptor pathway substrate 8 antigen. ". Cancer Immunol Immunother. 2015. PMID 25376540.
• "Eps8 regulates cellular proliferation and migration of breast cancer. ". Int J Oncol. 2015. PMID 25333707.
• "Real-time quantitative polymerase chain reaction assay for detecting the eps8 gene in acute myeloid leukemia.". Clin Lab. 2013. PMID 24409660.