EPOR

EPOR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CN4, 1EBA, 1EBP, 1EER, 1ERN, 2JIX, 2MV6, 4Y5V, 4Y5X, 4Y5Y
Dynodwyr
Cyfenwau	EPOR, EPO-R, erythropoietin receptor
Dynodwyr allanol	OMIM: 133171 HomoloGene: 95 GeneCards: EPOR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • identical protein binding • GO:0016518 cytokine receptor activity • transmembrane signaling receptor activity • erythropoietin receptor activity Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • extracellular region Prosesau biolegol • cytokine-mediated signaling pathway • heart development • brain development • decidualization • GO:0072468 signal transduction • erythropoietin-mediated signaling pathway • positive regulation of phosphatidylinositol 3-kinase signaling • positive regulation of Ras protein signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2057	n/a
Ensembl	ENSG00000187266	n/a
UniProt	P19235	n/a
RefSeq (mRNA)	NM_000121	n/a
RefSeq (protein)	NP_000112	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EPOR yw EPOR a elwir hefyd yn Erythropoietin receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EPOR.

• EPO-R

Llyfryddiaeth

• "Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. ". Lipids Health Dis. 2016. PMID 27640183.
• "Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro. ". J Hematol Oncol. 2016. PMID 27581518.
• "A new point mutation in EPOR inducing a short deletion in congenital erythrocytosis. ". Br J Haematol. 2016. PMID 26010769.
• "Erythropoietin Receptor Antagonist Suppressed Ectopic Hemoglobin Synthesis in Xenografts of HeLa Cells to Promote Their Destruction. ". PLoS One. 2015. PMID 25874769.
• "Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe.". Oncotarget. 2015. PMID 25544764.