EMSY

EMSY
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UTU, 1UZ3, 2FMM
Dynodwyr
Cyfenwau	EMSY, GL002, C11orf30, BRCA2 interacting transcriptional repressor, EMSY transcriptional repressor, BRCA2 interacting
Dynodwyr allanol	OMIM: 608574 HomoloGene: 32465 GeneCards: EMSY
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • protein homodimerization activity Cydrannau o'r gell • cnewyllyn cell • nucleoplasm Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • GO:0100026 DNA repair • transcription, DNA-templated • cellular response to DNA damage stimulus • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	56946	n/a
Ensembl	ENSG00000158636	n/a
UniProt	Q7Z589	n/a
RefSeq (mRNA)	NM_001300942 NM_001300943 NM_001300944 NM_020193	n/a
RefSeq (protein)	NP_001287871 NP_001287872 NP_001287873 NP_064578	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EMSY yw EMSY a elwir hefyd yn EMSY, BRCA2 interacting transcriptional repressor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.5.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EMSY.

• GL002
• C11orf30

Llyfryddiaeth

• "EMSY promoted the growth and migration of ovarian cancer cells. ". Tumour Biol. 2015. PMID 25510665.
• "Expression of EMSY, a novel BRCA2-link protein, is associated with lymph node metastasis and increased tumor size in breast carcinomas. ". Asian Pac J Cancer Prev. 2014. PMID 24641409.
• "The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair. ". Oncotarget. 2017. PMID 28099152.
• "EMSY copy number variation in male breast cancers characterized for BRCA1 and BRCA2 mutations. ". Breast Cancer Res Treat. 2016. PMID 27628328.
• "The locus C11orf30 increases susceptibility to poly-sensitization.". Allergy. 2015. PMID 25546184.